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Structural Alignment: A Graph-Theoretic Approach
Structural alignment is the process of finding similarities between a pair of proteins based on their three-dimensional shape. Accurate detection of such similarities could reveal evolutionary relationships and predict the functions of different proteins. Despite the existing algorithms, the protein structure alignment problem is not completely solved. In this work a graph-theoretic a... zur Produkt-Seite
4813589 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MTQ4MDk1X0daT3AzLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MTQ4MDk1X0daT3AzLXBuZw==","post_title":"Structural Alignment: A Graph-Theoretic Approach","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24490973737&a=401125&m=11816&pref1=9783639279368","labels":[],"brand_id":1,"post_content":"Structural alignment is the process of finding similarities between a pair of proteins based on their three-dimensional shape. Accurate detection of such similarities could reveal evolutionary relationships and predict the functions of different proteins. Despite the existing algorithms, the protein structure alignment problem is not completely solved. In this work a graph-theoretic approach is considered, which consists of representing tertiary protein structures as labeled graphs, and interpreting the structural alignment problem as a particular case of the Maximum Common Subgraph (MCS) problem. Our algorithm was then implemented under parallel platforms using a combination of threads and message passing techniques. Experiments were performed on a set of proteins selected randomly from the Protein Data Bank. The experiments proved the time- efficiency and accuracy of our method when compared to several other algorithms.","merchants_number":1,"ean":9783639279368,"category_id":103,"size":null,"min_price":47.39999999999999857891452847979962825775146484375,"low_price_merchant_id":1087639,"ID":4813589,"merchants":["dodax"],"brand":"undefined","slug":"structural-alignment-a-graph-theoretic-approach","url":"\/unterhaltung\/produkt\/structural-alignment-a-graph-theoretic-approach\/","low_price_merchant_name":null}
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Photochemie und Signaltransduktion von Blaulichtrezeptorproteinen
Die lichtaktivierte Kinase Phototropin aus Chlamydomonas reinhardtii, die photoaktivierte Adenylatcyclase (PAC) aus Euglena gracilis und das BLUF-Protein Slr1694 aus Synechocystis sp. PCC 6803 wurden in Hinblick auf die molekularen Details der primären photochemischen Prozesse sowie der Signalweiterleitung untersucht. Die Anwendung von Absorptions-, Fluoreszenz- und Elektronenspinreso... zur Produkt-Seite
4820933 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MjM1OTgzX09MWWJyLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MjM1OTgzX09MWWJyLXBuZw==","post_title":"Photochemie und Signaltransduktion von Blaulichtrezeptorproteinen","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24464913675&a=401125&m=11816&pref1=9783639000924","labels":[],"brand_id":1,"post_content":"Die lichtaktivierte Kinase Phototropin aus Chlamydomonas reinhardtii, die photoaktivierte Adenylatcyclase (PAC) aus Euglena gracilis und das BLUF-Protein Slr1694 aus Synechocystis sp. PCC 6803 wurden in Hinblick auf die molekularen Details der prim\u00e4ren photochemischen Prozesse sowie der Signalweiterleitung untersucht. Die Anwendung von Absorptions-, Fluoreszenz- und Elektronenspinresonanzspektroskopie erzielte molekulare Einblicke in die Photochemie, die strukturelle Anordnung der Proteindom\u00e4nen sowie die Dynamik von Kofaktor und Protein. Die zeitaufgel\u00f6sten Methoden erm\u00f6glichten eine umfassende Beschreibung der Photoreaktionen von der Absorption eines Photons innerhalb von Femtosekunden bis hin zur Bildung eines langlebigen Signalzustandes. Durch gezielte Proteinmodifikationen wurden zus\u00e4tzlich Informationen zur Kofaktorbindung sowie zur Farbverschiebung der Proteine erhalten.","merchants_number":1,"ean":9783639000924,"category_id":103,"size":null,"min_price":60.60000000000000142108547152020037174224853515625,"low_price_merchant_id":1087639,"ID":4820933,"merchants":["dodax"],"brand":"undefined","slug":"photochemie-und-signaltransduktion-von-blaulichtrezeptorproteinen","url":"\/unterhaltung\/produkt\/photochemie-und-signaltransduktion-von-blaulichtrezeptorproteinen\/","low_price_merchant_name":null}
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Camel Clinical Biochemistry and Hematology
1. Introduction.- 2. Hematology.- 3. Energetic Parameters.- 4. Nitrogen and Protein Parameters.- 5. Clinical Enzymology.- 6. Macro-Minerals and Electrolytes.- 7. Trace Elements.- 8. Vitamins.- 9. Hormones.- 10. General Conclusion. zur Produkt-Seite
4829900 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNDIvMjgvYzMvNzA5ODMyOTcwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNDIvMjgvYzMvNzA5ODMyOTcwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Camel Clinical Biochemistry and Hematology","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9783319955605&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F477263%2Fcamel-clinical-biochemistry-and-hematology%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"1. Introduction.- 2. Hematology.- 3. Energetic Parameters.- 4. Nitrogen and Protein Parameters.- 5. Clinical Enzymology.- 6. Macro-Minerals and Electrolytes.- 7. Trace Elements.- 8. Vitamins.- 9. Hormones.- 10. General Conclusion.","merchants_number":1,"ean":9783319955605,"category_id":103,"size":null,"min_price":178,"low_price_merchant_id":70255345,"ID":4829900,"merchants":["euniverse"],"brand":"undefined","slug":"camel-clinical-biochemistry-and-hematology","url":"\/unterhaltung\/produkt\/camel-clinical-biochemistry-and-hematology\/","low_price_merchant_name":"eUniverse"}
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Phytase supplementation in poultry
Phytic acid or phytate is an anti-nutritional constituent of plant derived feeds ,which forms a wide variety of insoluble salts with minerals like phosphorus, calcium, zinc, magnesium and copper. Phytic acid is also known to form complex with protein and proteolytic enzymes (pepsin and trypsin). Because of lack of endogenous phytase enzyme, which hydrolyzes phytic acid, phosphorus, ca... zur Produkt-Seite
4488632 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTM3MTQ1MDU2X1dYbEJPLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTM3MTQ1MDU2X1dYbEJPLXBuZw==","post_title":"Phytase supplementation in poultry","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=22948095159&a=401125&m=11816&pref1=9783330350564","labels":[],"brand_id":1,"post_content":"Phytic acid or phytate is an anti-nutritional constituent of plant derived feeds ,which forms a wide variety of insoluble salts with minerals like phosphorus, calcium, zinc, magnesium and copper. Phytic acid is also known to form complex with protein and proteolytic enzymes (pepsin and trypsin). Because of lack of endogenous phytase enzyme, which hydrolyzes phytic acid, phosphorus, calcium, protein and other bound nutrients are biologically less available to poultry. Microbial phytase has great nutritional significance and ecological importance. Poultry diets supplemented with microbial phytase result in improved growth performance and increased digestibility and availability of phytate bound phosphors, calcium, zinc and copper. Microbial phytase supplementation has also been shown to increase ileal digestibility of crude protein and amino acids. The efficacy of supplemental microbial phytase depends on its rate of inclusion, dietary calcium and phosphorus ratio, vitamin D3, nature of diet, and age and genotype of birds. Thus, microbial phytase is an efficient tool to exploit the inherent nutritional potential of feedstuffs for economic and eco-friendly poultry production.","merchants_number":1,"ean":9783330350564,"category_id":103,"size":null,"min_price":51.2000000000000028421709430404007434844970703125,"low_price_merchant_id":1087639,"ID":4488632,"merchants":["dodax"],"brand":"undefined","slug":"phytase-supplementation-in-poultry","url":"\/unterhaltung\/produkt\/phytase-supplementation-in-poultry\/","low_price_merchant_name":null}
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Reporter Genes
Table of contentsPreface. Donald S. Anson.1. Methodologies for staining and visualisation of '-galactosidase inembryos and tissues. Siobhan Loughna* and Deborah Henderson.2. Immunohistochemical Detection of Beta-Galactosidase or GreenFluorescence Protein on Tissue Sections. Philip A. Seymour and MaikeSander*.3. Detection of Reporter Gene Expression in Murine Airways. MariaLimberis*, P... zur Produkt-Seite
4214117 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZjQvNTgvNzkvMjk0ODcyNTAwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZjQvNTgvNzkvMjk0ODcyNTAwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Reporter Genes","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781588297396&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F379877%2Freporter-genes-a-practical-guide%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Table of contentsPreface. Donald S. Anson.1. Methodologies for staining and visualisation of '-galactosidase inembryos and tissues. Siobhan Loughna* and Deborah Henderson.2. Immunohistochemical Detection of Beta-Galactosidase or GreenFluorescence Protein on Tissue Sections. Philip A. Seymour and MaikeSander*.3. Detection of Reporter Gene Expression in Murine Airways. MariaLimberis*, Peter Bell, and James M. Wilson.4. Three dimensional analysis of molecular signals with episcopicimaging techniques. Wolfgang J. Weninger* & Timothy J. Mohun5. Fluorescent proteins for cell biology. George H. Patterson*6. Detection of GFP during nervous system development in Drosophilamelanogaster. Karin Edoff, James S. Dods and Andrea H. Brand*7. Autofluorescent Proteins for Flow Cytometry. Charles G. Bailey andJohn E. J. Rasko*8. Fluorescent protein reporter systems for single cell measurements.Steven K. Dower*, Eva E. Qwarnstrom and Endre Kiss-Toth9. Subcellular Imaging of cancer cells in live mice. Robert M. Hoffman*10. Non-invasive Imaging of Molecular Events with BioluminescentReporter Genes in Living Subjects. Pritha Ray and Sanjiv Sam Gambhir*.11. Green Fluorescent Protein as a Tracer in Chimeric Tissues. HaraldJockusch* and Daniel Eberhard","merchants_number":1,"ean":9781588297396,"category_id":103,"size":null,"min_price":153,"low_price_merchant_id":70255345,"ID":4214117,"merchants":["euniverse"],"brand":"undefined","slug":"reporter-genes","url":"\/unterhaltung\/produkt\/reporter-genes\/","low_price_merchant_name":"eUniverse"}
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Local Patterns in Biological Sequences
Many recent advances in the field of biology are due to the widespread and ever-increasing availability of sequence data, both DNA and protein. Local Patterns in Biological Sequences presents three different algorithms that make use of this wealth of information: CYRCA, HexDiff, and PreCUSA. CYRCA was designed to detect weak sequence similarity between protein families using conserved... zur Produkt-Seite
4767288 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/","post_title":"Local Patterns in Biological Sequences","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=36077252447&a=401125&m=13971&pref1=9783639101614","labels":[],"brand_id":1,"post_content":"Many recent advances in the field of biology are due to the widespread and ever-increasing availability of sequence data, both DNA and protein. Local Patterns in Biological Sequences presents three different algorithms that make use of this wealth of information: CYRCA, HexDiff, and PreCUSA. CYRCA was designed to detect weak sequence similarity between protein families using conserved protein sequence patterns and graph theory. HexDiff used frequencies of DNA patterns to detect a specific type of regulatory sequence called cis-regulatory modules. The third approach, drawing on the ideas explored in CYRCA and HexDiff, used structural attributes predicted from DNA sequence as an alternative source of information for detecting regulatory sequences in the genome. The common theme for these three algorithms is extracting local features from long biological sequences and utilizing them to predict large-scale sequence properties.","merchants_number":1,"ean":9783639101614,"category_id":103,"size":null,"min_price":69.900000000000005684341886080801486968994140625,"low_price_merchant_id":70254503,"ID":4767288,"merchants":["orell-fuessli"],"brand":"undefined","slug":"local-patterns-in-biological-sequences","url":"\/unterhaltung\/produkt\/local-patterns-in-biological-sequences\/","low_price_merchant_name":"Orell F\u00fcssli"}
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High-throughput Microfluidic Proteomics
Proteomics discovery holds the key to understanding biological process. Yet, millions of proteins with varied modifications and dynamic abundance pose a daunting measurement challenge. Facing the sea of proteins, the multiple sample preparation is the critical bottleneck which limits the power and speed of proteomics discovery. It is urgently calling for automatic, high throughput, an... zur Produkt-Seite
4314767 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTUyODA4NDQ1X2JOWEFQLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTUyODA4NDQ1X2JOWEFQLXBuZw==","post_title":"High-throughput Microfluidic Proteomics","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=22944356157&a=401125&m=11816&pref1=9783844380286","labels":[],"brand_id":1,"post_content":"Proteomics discovery holds the key to understanding biological process. Yet, millions of proteins with varied modifications and dynamic abundance pose a daunting measurement challenge. Facing the sea of proteins, the multiple sample preparation is the critical bottleneck which limits the power and speed of proteomics discovery. It is urgently calling for automatic, high throughput, and multiplexed protein processing platform. This book, therefore, introduces a state of the art of microfluidic technology for high-throughput proteomics. The functional nanoporous structures were created in microfluidic scale to form a new generation of multiple protein processing platform, including the preparatory (i.e., separation) and biological functions (i.e., enzymatic digestion). Such lithographically defined polymer materials possess the scaling-up capability for parallel, high-throughput protein processing. The strategy developed here should shed light on the advanced proteomics and glycomics, and should be especially useful to the exciting field of biomarker discovery, or anyone else who may be considering utilizing biotechnology for rapid, and ultra-low sample assay.","merchants_number":1,"ean":9783844380286,"category_id":103,"size":null,"min_price":60.60000000000000142108547152020037174224853515625,"low_price_merchant_id":1087639,"ID":4314767,"merchants":["dodax"],"brand":"undefined","slug":"high-throughput-microfluidic-proteomics","url":"\/unterhaltung\/produkt\/high-throughput-microfluidic-proteomics\/","low_price_merchant_name":null}
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Arabidopsis Protocols
Part I. Growing Arabidopsis 1. Handling Arabidopsis Plants: Growth, Preservation of Seeds, Transformation and Genetic CrossesLuz Rivero, Randy Scholl, Nicholas Holomuzki, Deborah Crist, Erich Grotewold, and Jelena Brkljacic 2. Using Arabidopsis Related Model Species (ARMS): Growth, Genetic Transformation and Comparative GenomicsGiorgia Batelli, Dong-Ha Oh, Matilde Paino D'Urzo, France... zur Produkt-Seite
4394849 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZDkvZWEvZjQvMzg2MzY4MjEwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZDkvZWEvZjQvMzg2MzY4MjEwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Arabidopsis Protocols","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781627035798&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F381385%2Farabidopsis-protocols%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Part I. Growing Arabidopsis 1. Handling Arabidopsis Plants: Growth, Preservation of Seeds, Transformation and Genetic CrossesLuz Rivero, Randy Scholl, Nicholas Holomuzki, Deborah Crist, Erich Grotewold, and Jelena Brkljacic 2. Using Arabidopsis Related Model Species (ARMS): Growth, Genetic Transformation and Comparative GenomicsGiorgia Batelli, Dong-Ha Oh, Matilde Paino D'Urzo, Francesco Orsini, Maheshi Dassanayake, Jian-Kang Zhu, Hans J. Bohnert, Ray A. Bressan and Albino Maggio 3. Growing Arabidopsis in vitro: Cell Suspensions, in vitro Culture, and RegenerationBronwyn J. Barkla, Rosario Vera-Estrella, and Omar Pantoja Part II. Arabidopsis resources 4. Arabidopsis Database and Stock ResourcesDonghui Li, Kate Dreher, Emma Knee, Jelena Brkljacic, Erich Grotewold, Tanya Z. Berardini, Philippe Lamesch, Margarita Garcia-Hernandez, Leonore Reiser and Eva Huala 5. Bioinformatic Tools in Arabidopsis ResearchMiguel de Lucas, Nicholas J. Provart, and Siobhan Brady Part III. Genetic techniques 6. Exploiting Natural Variation in ArabidopsisJohanna A. Molenaar and Joost J. B. Keurentjes 7. Grafting in ArabidopsisKatherine Bainbridge, Tom Bennett, Peter Crisp, Ottoline Leyser, and Colin Turnbull 8. Agrobacterium tumefaciens Mediated Transient Transformation of Arabidopsis thaliana LeavesSilvina Mangano, Cintia Daniela Gonz\u00e1lez, and Silvana Petruccelli 9. iTilling: Personalized Mutation ScreenSusan M. Bush and Patrick J. Krysan 10. Tailor Made Mutations in Arabidopsis Using Zinc-Finger NucleasesYiping Qi, Colby G. Starker, Feng Zhang, Nicholas J. Baltes, and Daniel F. Voytas 11. The Use of Artificial Micro RNA Technology to Control Gene Expression in Arabidopsis thalianaAndrew L. Eamens, Marcus McHale, and Peter M. Waterhouse 12. Generation and Identification of Arabidopsis EMS MutantsLi-Jia Qu and Gengi Qin 13. Generation and Identification of Arabidopsis T-DNA Insertion MutantsLi-Jia Qu and Gengi Qin 14. Identification of EMS-induced Causal Mutations in Arabidopsis thaliana by Next-Generation SequencingNaoyuki Uchida, Tomoaki Sakamoto, Masao Tasaka, and Tetsuya Kurata 15. Arabidopsis Transformation with Large Bacterial Artificial Chromosomes Jose M. Alonso and Anna N. Stepanova 16. Global DNA Methylation Analysis Using Methyl-Sensitive Amplification Polymorphism (MSAP)Mahmoud W. Yaish, Mingsheng Peng, and Steven J. Rothstein Part IV. Molecular biological techniques 17. Next Generation Mapping of Genetic Mutations Using Bulk Population SequencingRyan S. Austin, Steven P. Chatfield, Darrell Desveaux, and David S. Guttman 18. Chemical Fingerprinting of Arabidopsis Using Fourier-transform Infrared (FT-IR) Spectroscopic Approaches Andr\u00e1s Gorzs\u00e1s and Bj\u00f6rn Sundberg 19. A Pipeline for 15N Metabolic Labeling and Phosphoproteome Analysis in Arabidopsis thalianaBenjamin B. Minkoff, Heather L. Burch, and Michael R. Sussman 20. Gene Expression Profiling Using DNA MicroarraysKionoshin Maruyama, Kazuko Yamaguchi-Shinozaki, and Kazuo Shinozaki 21. Forward Chemical Genetic Screening Hyunmo Choi, Jun-Young Kim, Young Tae Chang, and Hong Gil Nam 22. Highly-Reproducible ChIP-On-Chip Analysis to Identify Genome-Wide Protein Binding and Chromatin Status in Arabidopsis thalianaJong-Myong Kim, Taiko Kim To, Maho Tanaka, Takaho A. Endo, Akihiro Matsui, Junko Ishida, Fiona C. Robertson, Tetsuro Toyoda, and Motoaki Seki Part V. Cell biological techniques 23. Fluorescence MicroscopySebastien Peter, Klaus Harter, and Frank Schleifenbaum 24. Immunocytochemical Fluorescent In Situ Visualization of Proteins in Arabidopsis Yohann Boutt\u00e9 and Markus Grebe 25. High Pressure Freezing and Freeze Substitution of Arabidopsis For Electron MicroscopyJotham R. Austin, II. 26. Applications of Fluorescent Marker Proteins in Plant Cell BiologyMichael R. Blatt and Christopher Grefen 27. Flow Cytometry and Sorting in ArabidopsisDavid W. Galbraith 28. Live Imaging of Arabidopsis Development Daniel von Wangenheim, Gabor Daum, Jan U. Lohmann , Ernst K. Stelzer, and Alexis Maizel 29. Arabidopsis Organelle Isolation and CharacterisationNicolas L. Taylor, Elke Str\u00f6her, and A. Harvey Millar Part VI. Biochemical and physiological techniques 30. Analysis of Subcellular Metabolite Distributions within Arabidopsis thaliana Leaf Tissue: A Primer for Subcellular MetabolomicsStephan Krueger, Dirk Steinhauser, Jan Lisec, and Patrick Giavalisco 31. Hormone ProfilingGaetan Glauser, Armelle Vallat, and Dirk Balmer 32. Purification of Protein Complexes and Characterization of Protein-Protein InteractionsKirby N. Swatek, Chris B. Lee, and Jay J. Thelen 33. Protein Fragment Bimolecular Fluorescence Complementation Analysis for the In vivo Study of Protein-Protein Interactions and Cellular Protein Complex LocalizationsRainer Waadt, Kathrin Schl\u00fckling, Julian I. Schroeder, and J\u00f6rg Kudla 34. The Split Ubiquitin System for the Analysis of Three-Component InteractionsChristopher Grefen 35. RNA-Binding Protein Immunoprecipitation from Whole Cell ExtractsTino K\u00f6ster and Dorothee Staiger 36. High Throughput Analysis of Protein-DNA Binding AffinityJos\u00e9 M. Franco-Zorrilla and Roberto Solano","merchants_number":1,"ean":9781627035798,"category_id":103,"size":null,"min_price":239,"low_price_merchant_id":70255345,"ID":4394849,"merchants":["euniverse"],"brand":"undefined","slug":"arabidopsis-protocols","url":"\/unterhaltung\/produkt\/arabidopsis-protocols\/","low_price_merchant_name":"eUniverse"}
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Phosphorylase Kinase
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Phosphorylase kinase is a serine/threonine-specific protein kinase which converts glycogen phosphorylase b to glycogen phosphorylase a, activating it to release glucose-1-phosphate from glycogen. The protein is a homotetramer of tetramers, which each of the f... zur Produkt-Seite
5145887 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MjI4MzExXzhHamc5LXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MjI4MzExXzhHamc5LXBuZw==","post_title":"Phosphorylase Kinase","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24447758063&a=401125&m=11816&pref1=9786130965334","labels":[],"brand_id":1,"post_content":"Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Phosphorylase kinase is a serine\/threonine-specific protein kinase which converts glycogen phosphorylase b to glycogen phosphorylase a, activating it to release glucose-1-phosphate from glycogen. The protein is a homotetramer of tetramers, which each of the four tetramers possessing an , , , and subunit. The (gamma) subunit is the site of the enzyme''s catalytic activity, i.e. the conversion of glycogen phosphorylase b to glycogen phosphorylase a. The other three subunits regulate the enzyme''s activity and, when unmodified by the binding of calcium or phosphorylation, are inhibitory.","merchants_number":1,"ean":9786130965334,"category_id":103,"size":null,"min_price":28.800000000000000710542735760100185871124267578125,"low_price_merchant_id":1087639,"ID":5145887,"merchants":["dodax"],"brand":"undefined","slug":"phosphorylase-kinase","url":"\/unterhaltung\/produkt\/phosphorylase-kinase\/","low_price_merchant_name":null}
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CFTR and Cystic Fibrosis
Cystic fibrosis: an overview.- CFTR gene and protein.- CFTR in the cell.- CFTR function.- Therapies aimed at correcting the basic defect. zur Produkt-Seite
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Signal Transduction
Signal transduction. Integrin, Ligand-gated ion channel, Intracellular receptor, G protein-coupled receptor, GTPase, Phosphatase, Redox signaling, Receptor tyrosine kinase, Toll-like receptor, Membrane receptor, Chemokine receptor, Adrenergic receptor, Insulin, Second messenger system. zur Produkt-Seite
4650578 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtODY4ODI0NDlfUkFqZWItcG5n!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtODY4ODI0NDlfUkFqZWItcG5n","post_title":"Signal Transduction","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=22940127013&a=401125&m=11816&pref1=9786130037208","labels":[],"brand_id":1,"post_content":"Signal transduction. Integrin, Ligand-gated ion channel, Intracellular receptor, G protein-coupled receptor, GTPase, Phosphatase, Redox signaling, Receptor tyrosine kinase, Toll-like receptor, Membrane receptor, Chemokine receptor, Adrenergic receptor, Insulin, Second messenger system.","merchants_number":1,"ean":9786130037208,"category_id":103,"size":null,"min_price":32.5499999999999971578290569595992565155029296875,"low_price_merchant_id":1087639,"ID":4650578,"merchants":["dodax"],"brand":"undefined","slug":"signal-transduction","url":"\/unterhaltung\/produkt\/signal-transduction\/","low_price_merchant_name":null}
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PEGylation
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. PEGylation is the process of covalent attachment of Polyethylene glycol polymer chains to another molecule, normally a drug or therapeutic protein. PEGylation is routinely achieved by incubation of a reactive derivative of PEG with the target macromolecule. T... zur Produkt-Seite
5281520 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MjIxMDE4X3BZMmxkLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MjIxMDE4X3BZMmxkLXBuZw==","post_title":"PEGylation","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24447726767&a=401125&m=11816&pref1=9786130962142","labels":[],"brand_id":1,"post_content":"Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. PEGylation is the process of covalent attachment of Polyethylene glycol polymer chains to another molecule, normally a drug or therapeutic protein. PEGylation is routinely achieved by incubation of a reactive derivative of PEG with the target macromolecule. The covalent attachment of PEG to a drug or therapeutic protein can \"mask\" the agent from the host''s immune system (reduced immunogenicity and antigenicity), increase the hydrodynamic size (size in solution) of the agent which prolongs its circulatory time by reducing renal clearance. PEGylation can also provide water solubility to hydrophobic drugs and proteins.","merchants_number":1,"ean":9786130962142,"category_id":103,"size":null,"min_price":32.5499999999999971578290569595992565155029296875,"low_price_merchant_id":1087639,"ID":5281520,"merchants":["dodax"],"brand":"undefined","slug":"pegylation","url":"\/unterhaltung\/produkt\/pegylation\/","low_price_merchant_name":null}
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Reviews in Fluorescence 2008
Fluorescence Anisotropy to Study the Preferential Orientation of Fluorophores in Ordered Bi-Dimensional Systems: Rhodamine 6G/Laponite Layered Films.- Room Temperature Tryptophan Phosphorescence of Proteins in the Composition of Biological Membranes and Solutions.- Rational Design of FRET-Based Sensor Proteins.- Fluorescence Imaging of Calcium Loading and Mitochondrial Depolarization ... zur Produkt-Seite
5503148 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvcmV2aWV3cy1pbi1mbHVvcmVzY2VuY2UtMjAwOC0yNzgxODU1MjQuanBn!aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvcmV2aWV3cy1pbi1mbHVvcmVzY2VuY2UtMjAwOC0yNzgxODU1MjQuanBnfH58aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMGUvZjkvNzYvMjMzODE5NTEwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Reviews in Fluorescence 2008","deeplink":"https:\/\/track.adtraction.com\/t\/t?a=1632201226&as=1592767275&t=2&tk=1&url=https:\/\/www.weltbild.ch\/artikel\/x\/_16107285-1","labels":[],"brand_id":1,"post_content":"Fluorescence Anisotropy to Study the Preferential Orientation of Fluorophores in Ordered Bi-Dimensional Systems: Rhodamine 6G\/Laponite Layered Films.- Room Temperature Tryptophan Phosphorescence of Proteins in the Composition of Biological Membranes and Solutions.- Rational Design of FRET-Based Sensor Proteins.- Fluorescence Imaging of Calcium Loading and Mitochondrial Depolarization in Cancer Cells Exposed to Heat Stress.- Energy Transfer in Silica Nanoparticles: An Essential Tool for the Amplification of the Fluorescence Signal.- Spectroscopic Characterization of Plasma - Chemically Functionalized and Fluorophore-Labeled Polymer Surfaces.- Fluorescent Labeling and Its Effect on Hybridization of Oligodeoxyribonucleotides.- New Method for Determining Histamine Rate in Halieutic Products.- Spectroscopy of DNA-Actinomycin Complexes.- Fluorescence Spectroscopy in Optoelectronics, Photomedicine, and Investigation of Biomolecular Systems.- Multicolor Imaging with Fluorescent Proteins in Mice.- Genetically Encoded Fluorescent and Bioluminescent Probes for Illuminating Cellular Signaling Pathways.- Fluorescent Protein FRET Applications.- Imaging Protein Interactions in Living Cells Using the Fluorescent Proteins.- Engineering Green Fluorescent Proteins Using an Expanded Genetic Code.- Fluorescent Proteins in Transgenic Plants.- Peptide Foldamers: From Spectroscopic Studies to Applications.- Circularly Polarized Luminescence (CPL) of Proteins and Protein Complexes.- New Dual Fluorescent Dyes Based on Modified \"Excited State with Extended Conjunction\" Photophysical Model.- Erratum.","merchants_number":2,"ean":9781441908285,"category_id":103,"size":null,"min_price":236,"low_price_merchant_id":27291482,"ID":5503148,"merchants":["weltbild","euniverse"],"brand":"undefined","slug":"reviews-in-fluorescence-2008","url":"\/unterhaltung\/produkt\/reviews-in-fluorescence-2008\/","low_price_merchant_name":"Weltbild"}
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Nuclear-cytoplasmic translocation of the transporter regulator RS1
The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and regulation of confluence-dependent nuclear location of RS1 was investigated. Nuclear location of RS1 was found to be regulated by the cell cycle. A nuclear shuttling signal (NS) in pRS1 was identified that mediates translocation of RS1 into... zur Produkt-Seite
4256630 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTM4MTc2MDQ1X3ZxdmdxLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTM4MTc2MDQ1X3ZxdmdxLXBuZw==","post_title":"Nuclear-cytoplasmic translocation of the transporter regulator RS1","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=22935710985&a=401125&m=11816&pref1=9783838111612","labels":[],"brand_id":1,"post_content":"The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and regulation of confluence-dependent nuclear location of RS1 was investigated. Nuclear location of RS1 was found to be regulated by the cell cycle. A nuclear shuttling signal (NS) in pRS1 was identified that mediates translocation of RS1 into and out of the nucleus via importin \u00df1 and CRM1, respectively. The adjacent protein kinase C (PKC) phosphorylation site was shown to control nuclear localization driven by NS during confluence. According to the proposed model, in subconfluent cells, RS1 is actively imported into the nucleus whereas nuclear export of RS1 is not active. After confluence, phosphorylation of serine 370 of pRS1 by PKC takes place leading to enhancement of RS1 nuclear export and predominantly cytoplasmic distribution of the protein. Gene expression profiling of mouse embryonic fibroblasts with RS1-\/- genotype suggests that transcriptional regulation by RS1 might be important for the cell cycle and cell division. Thus, RS1 might play a role in the regulation of the solute carriers during specific phases of the cell cycle.","merchants_number":1,"ean":9783838111612,"category_id":103,"size":null,"min_price":59.5499999999999971578290569595992565155029296875,"low_price_merchant_id":1087639,"ID":4256630,"merchants":["dodax"],"brand":"undefined","slug":"nuclear-cytoplasmic-translocation-of-the-transporter-regulator-rs1","url":"\/unterhaltung\/produkt\/nuclear-cytoplasmic-translocation-of-the-transporter-regulator-rs1\/","low_price_merchant_name":null}
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Voltage- Dependent Anion Channel
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Voltage-dependent anion channels are a class of porin ion channel located on the outer mitochondrial membrane. This major protein of the outer mitochondrial membrane of eukaryotes. It forms a voltage-dependent anion-selective channel (VDAC) that behaves as a ... zur Produkt-Seite
5283812 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MzA3NzQ2X1FkTzZaLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTI4MzA3NzQ2X1FkTzZaLXBuZw==","post_title":"Voltage- Dependent Anion Channel","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24447717453&a=401125&m=11816&pref1=9786131044328","labels":[],"brand_id":1,"post_content":"Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Voltage-dependent anion channels are a class of porin ion channel located on the outer mitochondrial membrane. This major protein of the outer mitochondrial membrane of eukaryotes. It forms a voltage-dependent anion-selective channel (VDAC) that behaves as a general diffusion pore for small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. This protein contains about 280 amino acids and its sequence is composed of between 12 to 16 beta-strands that span the mitochondrial outer membrane.","merchants_number":1,"ean":9786131044328,"category_id":103,"size":null,"min_price":32.5499999999999971578290569595992565155029296875,"low_price_merchant_id":1087639,"ID":5283812,"merchants":["dodax"],"brand":"undefined","slug":"voltage-dependent-anion-channel","url":"\/unterhaltung\/produkt\/voltage-dependent-anion-channel\/","low_price_merchant_name":null}
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Myosins
List of contributors.- Structural and functional diversity of the myosin family of actin-based molecular motors.- Myosin structure .- The myosin family: biochemical and kinetic properties.- Myosin I.- Myosin II: Sarcomeric myosins, the motors of contraction in cardiac and skeletal muscles.- Smooth-muscle myosin II.- Non-muscle myosin II.- Class III Myosins.- Myosin V.- Myosin VI: a mu... zur Produkt-Seite
4922300 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNDkvM2UvYTYvMjk4MTg2MjAwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNDkvM2UvYTYvMjk4MTg2MjAwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Myosins","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781402065163&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F419342%2Fmyosins-a-superfamily-of-molecular-motors%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"List of contributors.- Structural and functional diversity of the myosin family of actin-based molecular motors.- Myosin structure .- The myosin family: biochemical and kinetic properties.- Myosin I.- Myosin II: Sarcomeric myosins, the motors of contraction in cardiac and skeletal muscles.- Smooth-muscle myosin II.- Non-muscle myosin II.- Class III Myosins.- Myosin V.- Myosin VI: a multifunctional motor protein.- Myosin VII.- Plant Myosins VIII, XI, and XIII.- Class IX Myosins Negative Regulators of the small GTP-binding Protein Rho.- Myosin X.- Myosin XIV and other myosins in protists.- Myosin XVa.- Index.","merchants_number":1,"ean":9781402065163,"category_id":103,"size":null,"min_price":299,"low_price_merchant_id":70255345,"ID":4922300,"merchants":["euniverse"],"brand":"undefined","slug":"myosins","url":"\/unterhaltung\/produkt\/myosins\/","low_price_merchant_name":"eUniverse"}
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A Method For Enrichment Of The secretory pathway
The purpose of this project is to optimize a method to allow a comprehensive identification of the proteomic profile of two organelles from wheat endosperm, endoplasmic reticulum and Golgi Complex. The method demonstrated a successful technique to enrich the target proteins and could serve as a model for investigating various complex organelles in crops. Improving crops quality requir... zur Produkt-Seite
5074256 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTcwMjUxNTU4X0tXZ2xHLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTcwMjUxNTU4X0tXZ2xHLXBuZw==","post_title":"A Method For Enrichment Of The secretory pathway","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24465311673&a=401125&m=11816&pref1=9783838379241","labels":[],"brand_id":1,"post_content":"The purpose of this project is to optimize a method to allow a comprehensive identification of the proteomic profile of two organelles from wheat endosperm, endoplasmic reticulum and Golgi Complex. The method demonstrated a successful technique to enrich the target proteins and could serve as a model for investigating various complex organelles in crops. Improving crops quality requires an attention to the biochemical process of its development and knowledge of the machinery involved in this development. The protein synthesis machinery involves both organelles which determine storage proteins quality during endosperm development. The rate of reserve material accumulation varies during the grain filling stages.The constitutive proteins of the ER and GC are speculated to undergo changes in function, and a temporal change in protein expression during these stages assumed to be related to wheat protein quality. Consequently, the identification of the organelles proteins could contribute to the process of genetic modification intended to improve the crop quality.","merchants_number":1,"ean":9783838379241,"category_id":103,"size":null,"min_price":50.2999999999999971578290569595992565155029296875,"low_price_merchant_id":1087639,"ID":5074256,"merchants":["dodax"],"brand":"undefined","slug":"a-method-for-enrichment-of-the-secretory-pathway","url":"\/unterhaltung\/produkt\/a-method-for-enrichment-of-the-secretory-pathway\/","low_price_merchant_name":null}
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Anti-tumorigenic activity of BML Proteases on cancerous tumor cells
BML proteases is a pharmacologically active compound, which has been shown to have anti-edematous, anti-inflammatory, anti-thrombotic and anti-metastatic properties. In the present study anti-tumorigenic activity of BML was recorded in MCF 7, PC3 and HeLa cell lines. Results proved that BML proteases application delayed the onset of tumorigenesis and reduced the cumulative number of t... zur Produkt-Seite
4616618 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTQ5NTE5ODk5XzlETE05LXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTQ5NTE5ODk5XzlETE05LXBuZw==","post_title":"Anti-tumorigenic activity of BML Proteases on cancerous tumor cells","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=30524831509&a=401125&m=11816&pref1=9783659459870","labels":[],"brand_id":1,"post_content":"BML proteases is a pharmacologically active compound, which has been shown to have anti-edematous, anti-inflammatory, anti-thrombotic and anti-metastatic properties. In the present study anti-tumorigenic activity of BML was recorded in MCF 7, PC3 and HeLa cell lines. Results proved that BML proteases application delayed the onset of tumorigenesis and reduced the cumulative number of tumors, tumor volume and the average number of tumor cells. To establish a cause and effect relationship, we targeted the proteins involved in the cell death pathway. BML proteases treatment resulted in regulation of p53 gene and subsequent activation of caspase 3 and caspase 9 with concomitant decrease in anti-apoptotic protein Bcl-2 in cancer cells. BML treatment attenuated phosphorylation of extracellular signal regulated protein kinase (ERK1\/2) and mitogen-activated protein kinase (MAPK). Taken together, we conclude that BML induces apoptosis related proteins by blocking the MAPK kinase signaling in tumor cells, which may account for its anti-tumorigenic effects.","merchants_number":1,"ean":9783659459870,"category_id":103,"size":null,"min_price":66.099999999999994315658113919198513031005859375,"low_price_merchant_id":1087639,"ID":4616618,"merchants":["dodax"],"brand":"undefined","slug":"anti-tumorigenic-activity-of-bml-proteases-on-cancerous-tumor-cells","url":"\/unterhaltung\/produkt\/anti-tumorigenic-activity-of-bml-proteases-on-cancerous-tumor-cells\/","low_price_merchant_name":null}
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Comparative Analysis of Contacts Between Crystal Lattice & Oligo Interface
G proteins are molecular amplifiers. GTPases are a large family of enzymes that can bind and hydrolyze GTP. The GTP binding and hydrolysis takes place in the highly conserved G domain common to all GTPases. Protein crystal contacts are weak and generally form only under conditions designed to limit protein solubility and maximize protein-2 interactions. However, they do form with a ki... zur Produkt-Seite
4762520 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTUxNTc2MDk1X0FQOU9hLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTUxNTc2MDk1X0FQOU9hLXBuZw==","post_title":"Comparative Analysis of Contacts Between Crystal Lattice & Oligo Interface","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24465663079&a=401125&m=11816&pref1=9783659914973","labels":[],"brand_id":1,"post_content":"G proteins are molecular amplifiers. GTPases are a large family of enzymes that can bind and hydrolyze GTP. The GTP binding and hydrolysis takes place in the highly conserved G domain common to all GTPases. Protein crystal contacts are weak and generally form only under conditions designed to limit protein solubility and maximize protein-2 interactions. However, they do form with a kind of specificity, at least in the sense that only certain contacts are repeated within each unit cell of any particular crystal packing arrangement. For oligomeric proteins, amino acids at the subunit interfaces have been selected in order to maintain affinity and specificity properties. Many proteins contain highly flexible or even completely unfolded fragments that dramatically interfere with crystallization conditions. These conditions are the crystal lattice and Oligomeric interface or proteins that allow the residues to bind in such a specific way by which the crystallization of GTPase is fast. This book therefore, should be helpful for better understanding the crystallograpgy of proteins for biologists etc.","merchants_number":1,"ean":9783659914973,"category_id":103,"size":null,"min_price":29.64999999999999857891452847979962825775146484375,"low_price_merchant_id":1087639,"ID":4762520,"merchants":["dodax"],"brand":"undefined","slug":"comparative-analysis-of-contacts-between-crystal-lattice-oligo-interface","url":"\/unterhaltung\/produkt\/comparative-analysis-of-contacts-between-crystal-lattice-oligo-interface\/","low_price_merchant_name":null}
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A STRUCTURE BASED DRUG DESIGN STUDY ON VEGFR-2 INHIBITORS
VEGF (Vascular Endothelial Growth Factor) is a potent angiogenic signal implicated with a key role in several pathological processes, including tumour vascularization, angiogenesis, and endothelial cell growth. The members of VEGF family bind to tyrosine kinase receptors on the cell surface to initiate a signalling cascade. VEGFR-2 is one such Receptor Tyrosine Kinase(RTK) that is fou... zur Produkt-Seite
4373375 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTcwMTI5NjkwX3lSZEFWLXBuZw==!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTcwMTI5NjkwX3lSZEFWLXBuZw==","post_title":"A STRUCTURE BASED DRUG DESIGN STUDY ON VEGFR-2 INHIBITORS","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=22935818571&a=401125&m=11816&pref1=9783844319897","labels":[],"brand_id":1,"post_content":"VEGF (Vascular Endothelial Growth Factor) is a potent angiogenic signal implicated with a key role in several pathological processes, including tumour vascularization, angiogenesis, and endothelial cell growth. The members of VEGF family bind to tyrosine kinase receptors on the cell surface to initiate a signalling cascade. VEGFR-2 is one such Receptor Tyrosine Kinase(RTK) that is found to mediate a majority of the cellular responses to VEGF. A structure based drug design study was performed on VEGFR-2 inhibitors based on the article \"Hetaryl imidazoles: A novel dual inhibitors of VEGF receptors 1 and 2\". The target protein was retrieved from the Protein Data Bank (I.D. 2OH4), based on the Ramachandran plot. The structures of reported inhibitors were obtained in 3-D format using standard software packages. These 3-D analogues were docked to the protein of choice using Molegro Virtual Docker. Based on a correlation between experimentally obtained log IC50 values and the results of the docking study, direct drug design was carried out. Novel inhibitors with significantly higher moldock scores were obtained with simple modifications to the original structure.","merchants_number":1,"ean":9783844319897,"category_id":103,"size":null,"min_price":50.2999999999999971578290569595992565155029296875,"low_price_merchant_id":1087639,"ID":4373375,"merchants":["dodax"],"brand":"undefined","slug":"a-structure-based-drug-design-study-on-vegfr-2-inhibitors","url":"\/unterhaltung\/produkt\/a-structure-based-drug-design-study-on-vegfr-2-inhibitors\/","low_price_merchant_name":null}
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Structural Alignment: A Graph-Theoretic Ap...
Structural alignment is the process of finding similarities between a pair of proteins based on their three-dimensional shape. Accurate detection o...
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Photochemie und Signaltransduktion von Bla...
Die lichtaktivierte Kinase Phototropin aus Chlamydomonas reinhardtii, die photoaktivierte Adenylatcyclase (PAC) aus Euglena gracilis und das BLUF-P...
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Camel Clinical Biochemistry and Hematology
1. Introduction.- 2. Hematology.- 3. Energetic Parameters.- 4. Nitrogen and Protein Parameters.- 5. Clinical Enzymology.- 6. Macro-Minerals and Ele...
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Phytase supplementation in poultry
Phytic acid or phytate is an anti-nutritional constituent of plant derived feeds ,which forms a wide variety of insoluble salts with minerals like ...
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Reporter Genes
Table of contentsPreface. Donald S. Anson.1. Methodologies for staining and visualisation of '-galactosidase inembryos and tissues. Siobhan Loughna...
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Local Patterns in Biological Sequences
Many recent advances in the field of biology are due to the widespread and ever-increasing availability of sequence data, both DNA and protein. Loc...
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High-throughput Microfluidic Proteomics
Proteomics discovery holds the key to understanding biological process. Yet, millions of proteins with varied modifications and dynamic abundance p...
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Arabidopsis Protocols
Part I. Growing Arabidopsis 1. Handling Arabidopsis Plants: Growth, Preservation of Seeds, Transformation and Genetic CrossesLuz Rivero, Randy Scho...
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Phosphorylase Kinase
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Phosphorylase kinas...
undefined
CFTR and Cystic Fibrosis
Cystic fibrosis: an overview.- CFTR gene and protein.- CFTR in the cell.- CFTR function.- Therapies aimed at correcting the basic defect.
undefined
Signal Transduction
Signal transduction. Integrin, Ligand-gated ion channel, Intracellular receptor, G protein-coupled receptor, GTPase, Phosphatase, Redox signaling, ...
undefined
PEGylation
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. PEGylation is the p...
undefined
Reviews in Fluorescence 2008
Fluorescence Anisotropy to Study the Preferential Orientation of Fluorophores in Ordered Bi-Dimensional Systems: Rhodamine 6G/Laponite Layered Film...
undefined
Nuclear-cytoplasmic translocation of the t...
The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and ...
undefined
Voltage- Dependent Anion Channel
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Voltage-dependent a...
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Myosins
List of contributors.- Structural and functional diversity of the myosin family of actin-based molecular motors.- Myosin structure .- The myosin fa...
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A Method For Enrichment Of The secretory p...
The purpose of this project is to optimize a method to allow a comprehensive identification of the proteomic profile of two organelles from wheat e...
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Anti-tumorigenic activity of BML Proteases...
BML proteases is a pharmacologically active compound, which has been shown to have anti-edematous, anti-inflammatory, anti-thrombotic and anti-meta...
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Comparative Analysis of Contacts Between C...
G proteins are molecular amplifiers. GTPases are a large family of enzymes that can bind and hydrolyze GTP. The GTP binding and hydrolysis takes pl...
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A STRUCTURE BASED DRUG DESIGN STUDY ON VEG...
VEGF (Vascular Endothelial Growth Factor) is a potent angiogenic signal implicated with a key role in several pathological processes, including tum...