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Cardiomyopathies and Heart Failure
Contributors. Preface. I: Introductory Chapter. Cardiomyopathies and Heart Failure: Biomolecular, Infections and Immune Mechanisms, A. Matsumori. II: Cytokines in Cardiomyopathies and Heart Failure. 1. Chemokines and Cardiovascular Diseases, K. Matsushima, et al. 2. Negative Regulator of Cytokine Signaling (SOCS) Genes in Inflammation, I. Kinjyo, et al. 3. The Interleukin-6 Family of ... zur Produkt-Seite
4416476 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNGMvMTUvZWYvMzgwODYxNTYwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNGMvMTUvZWYvMzgwODYxNTYwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9jYXJkaW9teW9wYXRoaWVzLWFuZC1oZWFydC1mYWlsdXJlLTI3OTkzOTMxNS5qcGc=","post_title":"Cardiomyopathies and Heart Failure","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781461348658&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F366769%2Fcardiomyopathies-and-heart-failure-biomolecular-infectious-and-immune-mechanisms%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Contributors. Preface. I: Introductory Chapter. Cardiomyopathies and Heart Failure: Biomolecular, Infections and Immune Mechanisms, A. Matsumori. II: Cytokines in Cardiomyopathies and Heart Failure. 1. Chemokines and Cardiovascular Diseases, K. Matsushima, et al. 2. Negative Regulator of Cytokine Signaling (SOCS) Genes in Inflammation, I. Kinjyo, et al. 3. The Interleukin-6 Family of Cytokines and their Receptors in Patients with Congestive Heart Failure, K. Yamauchi-Takihara, et al. 4. Animal Model of Cardiomyopathy Due to Overexpression of TNF-alpha, T. Kubota. III: Autoimmunity in Cardiomyopathies and Heart Failure. 5. Myosin Autoreactive T Cells and Autoimmune Myocarditis: Lessons from the Disease Caused by Cardiac Myosin Peptide CM2, T. Izumi, et al. 6. Autoimmunity in Cardiomyopathies, M. Noutsias, et al. 7. Anti-G-Protein Coupled Cardiac Receptor Autoantibodies in Dilated Cardiomyopathy, M. Fu. 8. Clinical Significance of Circulating Cardiac Autoantibodies in Dilated Cardiomyopathy and Myocarditis, A.L.P. Caforio, W.J. McKenna. IV: Mast Cell Mediators and Human Diseases: Basic Aspects. 9. Development of Mast Cells: Process and Regulatory Mechanisms, Y. Kitamura, et al. 10. Mast Cells in Experimental Myocardial Infarction, N.G. Frangogiannis, M.L. Entman. 11. possible Involvement of Mast Cells in the Development of Fibrosis, M. Kurosawa, et al. 12. Human Mast Cell Chymase and 31 Amino Acid Endothelin-1, H. Kido, et al. 13. Tryptase from Human mast Cells, L.B. Schwartz. 14. Effects of the Tryptase Receptor Activating Peptide and Antibodies against the Tryptase Receptor PAR-2 on Neonatal Rat Cardiomyocytes in Culture, G. Wallukat, et al. V: Mast Cell Mediators and Human Diseases Clinical Aspects. 15. Role of Human Heart Mast Cells in Immunologic and Inflammatory Mechanisms Underlying Cardiovascular Disorders, G. Marone, et al. 16. Mast Cells in Atherosclerotic Human Coronary Arteries: Implications for Coronary Fatty Streak Formation and Plaque Erosion or Rupture, P.T. Kovanen, et al. 17. The Key Role of Mast Cells in the Evolution to Congestive Heart Failure, M. Hara, et al. VI: Viral Etiology of Cardiomyopathies and Heart Failure. 18. Links between Viral Infections and Heart Disease, C.J. Gauntt, et al. 19. Molecular Detection and Characterization of Human Enteroviruses, M.A. Pallansch, M.S. Oberste. 20. Detection and Biological Implications of Genetic Memeory in Viral Quasispecies, E. Domingo, et al. 21. The Group B Coxsackieviruses as Vaccines and Vectors, N.M. Chapman, et al. 22. Detection of Important Diagnostic Markers of HCV Infection, H.A. Fields. VII: Diagnosis and Treatment of Myocarditis. 23. Large Animal Model of Viral Myocarditis, M.K. Njenga, et al. 24. Hepatitis C Virus and Cardiomyopathy, Y. Sato, et al. 25. Diagnosis and Treatment of Myocarditis: The Role of Adenovirus Infection in Cardiomyopathy and Heart Failure, J.A. Towbin, N.E. Bowles. 26. The Natural History of Viral Myocarditis: Pathogenic Role of Adrenergic System Dysfunction in the Development of Idiopathic Dilated Cardiomyopathy, P.M. S","merchants_number":2,"ean":9781461348658,"category_id":103,"size":null,"min_price":168,"low_price_merchant_id":70255345,"ID":4416476,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"cardiomyopathies-and-heart-failure","url":"\/unterhaltung\/produkt\/cardiomyopathies-and-heart-failure\/","low_price_merchant_name":"eUniverse"}
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Current Views of Fatty Acid Oxidation and Ketogenesis
Preface & Dedication, P.A. Quant, S. Eaton. Historical overview. Cambridge, colleagues, carnitine and ketogenesis ......., P.K. Tubbs. Carnitine and carnitine acyltransferases. 1. Biogenesis of the rat liver mitochondrial carnitine palmitoyltransferase I, I. Cohen, et al. 2. Subcellular distribution of mitochondrial carnitine palmitoyltransferase I in rat liver: Evidence for a d... zur Produkt-Seite
4917854 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMjUvZGYvMzUvMjMzMTEyMjAwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMjUvZGYvMzUvMjMzMTEyMjAwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Current Views of Fatty Acid Oxidation and Ketogenesis","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9780306462009&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F356478%2Fcurrent-views-of-fatty-acid-oxidation-and-ketogenesis-from-organelles-to-point-mutations%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Preface & Dedication, P.A. Quant, S. Eaton. Historical overview. Cambridge, colleagues, carnitine and ketogenesis ......., P.K. Tubbs. Carnitine and carnitine acyltransferases. 1. Biogenesis of the rat liver mitochondrial carnitine palmitoyltransferase I, I. Cohen, et al. 2. Subcellular distribution of mitochondrial carnitine palmitoyltransferase I in rat liver: Evidence for a distinctive N-terminal structure of the microsomal but not the peroxisomal enzyme, V.A. Zammit,et al. 3. Topology of hepatic mitochondrial carnitine palmitoyltransferase I, K. Kashfi, G.A. Cook. 4. Possible involvement of cytoskeletal components in the control of hepatic carnitine palmitoyltransferase I activity, G. Velasco, et al. 5. Regulation of beta-oxidation and CPT I activity by 3-thia fatty acids in cultured rat hepatocytes, J. Sleboda, J. Bremer. 6. Carnitine acyltransferases and associated transport systems in the endoplasmic reticulum, N.M. Broadway, et al. 7. Reciprocal enzymatic interference of carnitine palmitoyl transferase I and glycerol-3-phosphate acyltransferase in purified liver mitochondria, F. Beauseigneur, et al. 8. Control of human muscle carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor , C. Mascar\u00f3, et al. 9. Kinetic investigation of carnitine palmitoyltransferases in homogenates of human skeletal muscle using L-aminocarnitine and malonyl-CoA, K. Hertel, et al. 10. Processing of carnitine octanoyltransferase pre-mRNAs by cis- and trans-splicing, C. Caudevilla, et al. 11. Selective modulation of carnitine long-chain acyltransferase activities: kinetics, inhibitors andactive sites of COT and CPT II, R.R. Ramsay, R.D. Gandour. 12. Confocal laser scanning microscopy of human skin fibroblasts showing transient expression of a green fluorescent carnitine palmitoyltransferase 1 fusion protein, F.R. van der Leij, et al. 13. Carnitine biosynthesis: purification of gamma-butyrobetaine from rat liver, F. Vaz, et al. Mitochondrial fatty acid oxidation and ketogenesis. 14. Hypolipidemic 3-thia fatty acids: Fatty acid oxidation and ketogenesis in rat liver under proliferation of mitochondria and peroxisomes, R.K. Berge, et al. 15. Molecular mechanisms of fatty acid &bgr,-oxidation enzyme catalysis, S.-Y. Yang, X.-Y. He. 16. Control of mitochondrial &bgr,-oxidation at the level of [NAD+]\/[NADH] and CoA acylation, S. Eaton, et al. 17. Production and export of acyl-carnitine esters by neonatal rat hepatocytes, S. Eaton, et al. 18. Tissue specific differences in intramitochondrial control of &bgr,-oxidation, S. Eaton, K. Bartlett. 19. Endotoxin-induced changes in very-low-density lipoprotein and myocardial utilisation of triacylglycerol from abnormal VLDL in the rat, D.G. Hole, et al. 20. Effect of valproic acid on the expression of acyl-CoA dehydrogenases in various tissues, M. Nagao, et al. 21. Formation of a human `electron transferring flavoprotein': medium chain acyl CoA dehydrogenase complex - preliminary evidence from crosslinking studies, A. Parker, P.C. Engel. 22. Cloning and regulation of peroxisome proliferator-induced acyl-CoA thioestereases from mouse liver, M. Hunt, et al. 23. Metabolic effects of 3-thia fatty acids in cancer cells, K.J. Tronstad,","merchants_number":1,"ean":9780306462009,"category_id":103,"size":null,"min_price":239,"low_price_merchant_id":70255345,"ID":4917854,"merchants":["euniverse"],"brand":"undefined","slug":"current-views-of-fatty-acid-oxidation-and-ketogenesis","url":"\/unterhaltung\/produkt\/current-views-of-fatty-acid-oxidation-and-ketogenesis\/","low_price_merchant_name":"eUniverse"}
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Cell Culture Techniques
1. Guidance on Good Cell Culture Practice (GCCP)Anna Bal-Price and Sandra Coecke2. Induced Pluripotent Stem Cells (iPSCs): An Emerging Model System for the Study of Human NeurotoxicologyM. Diana Neely, Andrew M. Tidball, Asad A. Aboud, Kevin C. Ess, and Aaron B. Bowman3. Neural Stem CellsRoshan Tofighi, Christoffer Tamm, Michaela Moors, and Sandra Ceccatelli4. Primary Cultures for Neu... zur Produkt-Seite
5478854 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZmYvY2UvOWEvNjc3MzgwOTcwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZmYvY2UvOWEvNjc3MzgwOTcwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9jZWxsLWN1bHR1cmUtdGVjaG5pcXVlcy0yNzg4NDM5NjEuanBn","post_title":"Cell Culture Techniques","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781493958139&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F377497%2Fcell-culture-techniques%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"1. Guidance on Good Cell Culture Practice (GCCP)Anna Bal-Price and Sandra Coecke2. Induced Pluripotent Stem Cells (iPSCs): An Emerging Model System for the Study of Human NeurotoxicologyM. Diana Neely, Andrew M. Tidball, Asad A. Aboud, Kevin C. Ess, and Aaron B. Bowman3. Neural Stem CellsRoshan Tofighi, Christoffer Tamm, Michaela Moors, and Sandra Ceccatelli4. Primary Cultures for Neurotoxicity TestingCarme Sol\u00e0, Rosa Crist\u00f2fol, Cristina Su\u00f1ol, and Coral Sanfeliu5. Preparation and Use of Serum-Free Aggregating Brain Cell Cultures for Routine Neurotoxicity ScreeningPaul Honegger and Marie-Gabrielle Zurich6. Cell Culture to Investigate Neurotoxicity and Neurodegeneration Utilizing Caenorhabditis elegans Michelle L. Tucci, Guy A. Caldwell, and Kim A. Caldwell7. Modeling the Blood-Brain BarrierMarie-Pierre Dehouck, Elodie Vandenhaute, Lucie Dehouck, Emmanuel Sevin, Anne-Marie Lenfant, Yannick Delplace, Doroth\u00e9e Hallier-Vanuxeem, Maxime Culot, and Rom\u00e9o Cecchelli8. In vitro Models of the Blood-C erebrospinal Fluid Barrier and T heir Use in Neurotoxicological ResearchNathalie Strazielle and Jean-Fran\u00e7ois Ghersi-Egea9. Introducing Cloned Genes into Cultured Neurons Providing Novel In vitro Models for Neuropathology and Neurotoxicity StudiesMarcelo Farina, Jordi Berenguer, Sebasti\u00e1n Pons, Jo\u00e3o Batista Teixeira da Rocha, and Michael Aschner10. P19 Embryonic Carcinoma Cell Line: A Model To Study Gene-Environment InteractionsJoseph Bressler, Cliona O'Driscoll, Cathleen Marshall, and Walter Kaufmann11. Signal Transduction and Neurotoxicity: What Can We Learn from Experimental Culture Systems?Lucio G. Costa, Gennaro Giordano, and Marina Guizzetti12. Neurite Degeneration in Human Neuronal SH-SY5Y Cells as an Indicator of AxonopathyAnna Forsby13. The Use of Differentiating N2a and C6 Cell Lines for Studies of Organophosphate ToxicityAlan J. Hargreaves, Magda Sachana, and John Flaskos14. Assessing Toxic Injuries of Experimental Therapeutics to the Crystalline Lens Using Lens Explant CultureMichael D. Aleo15. Necrosis, Apoptosis, and Autophagy: Mechanisms of Neuronal and Glial Cell DeathMichael Fricker and Aviva M. Tolkovsky16. Inflammation and Reactive Oxygen\/Nitrogen Species in Glial\/Neuronal CulturesJonas J. Neher, Guy C. Brown, Agnieszka Kinsner-Ovaskainen, and Anna Bal-Price17. Neuronal Oxidative Injury and Biomarkers of Lipid PeroxidationDejan Milatovic and Michael Aschner18. Analysis of Protein Targets by Oxidative Stress Using the Oxyblot and Biotin-Avidin-Capture MethodologyJeannette N. Stankowski, Simona G. Codreanu, Daniel C. Liebler, and BethAnn McLaughlin19. Catecholaminergic Cell Lines for the Study of Dopamine Metabolism and NeurotoxicityJuan Segura-Aguilar20. 13 C NMR Spectroscopy and Mass Spectrometry Analysis of Intermediary Metabolism in Cultured Neural CellsUrsula Sonnewald, Arne Schousboe, and Helle S. Waagepetersen21. Culture Models for the Study of Amino Acid Transport and MetabolismMarta Sidoryk-Wegrzynowicz and Michael Aschner22. Neurotransmitter Transporters and Anticonvulsant Drug DevelopmentArne Schousboe, Karsten K. Madsen, and H. Steve White23. Ion Channel Electrophysiology in Cultured NeuronsToshio Narahashi24. Neurotoxicity Assessment by Recording Electrical Activity from Neuronal Networks on Microelectrode Array NeurochipsDieter G. Weiss25. GABA A Receptor Binding and Ion Channel Function in Primary Neuronal Cultures for Neuropharmacology\/Neurotoxicity TestingCristina Su\u00f1ol and Daniel A. Garc\u00eda","merchants_number":2,"ean":9781493958139,"category_id":103,"size":null,"min_price":157,"low_price_merchant_id":70255345,"ID":5478854,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"cell-culture-techniques-2","url":"\/unterhaltung\/produkt\/cell-culture-techniques-2\/","low_price_merchant_name":"eUniverse"}
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ERK Signaling
1. How Genetics has Helped Piece Together the MAPK Signaling PathwayDariel Ashton-Beaucage and Marc Therrien2. In Vitro Enzyme Kinetics Analysis of EGFRZhihong Wang and Christine Candelora3. High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast CellsNobuo Yoshimoto and Shun'ichi Kuroda4. Structural Studies of ERK2 Protein ComplexesJohannes F. Weijman, Stef... zur Produkt-Seite
4909061 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvZXJrLXNpZ25hbGluZy0yNzM1NDA4MDUuanBn!aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvZXJrLXNpZ25hbGluZy0yNzM1NDA4MDUuanBnfH58aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvY2MvYWMvNGUvNTc4MDA2OTMwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"ERK Signaling","deeplink":"https:\/\/track.adtraction.com\/t\/t?a=1632201226&as=1592767275&t=2&tk=1&url=https:\/\/www.weltbild.ch\/artikel\/x\/_21678019-1","labels":[],"brand_id":1,"post_content":"1. How Genetics has Helped Piece Together the MAPK Signaling PathwayDariel Ashton-Beaucage and Marc Therrien2. In Vitro Enzyme Kinetics Analysis of EGFRZhihong Wang and Christine Candelora3. High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast CellsNobuo Yoshimoto and Shun'ichi Kuroda4. Structural Studies of ERK2 Protein ComplexesJohannes F. Weijman, Stefan J. Riedl, and Peter D. Mace5. Isolation and Characterization of Intrinsically Active (MEK-Independent) Mutants of Mpk1\/ErkTal Goshen-Lago, Dganit Melamed, Arie Admon, and David Engelberg6. Assaying Activation and Subcellular Localization of ERK in Cells and TissuesCarme Caelles, Carles Bayod, and Melisa Morcillo7. Detection and Functional Analysis of SUMO-Modified MEKYuji Kubota and Mutsuhiro Takekawa8. Single-Step Affinity Purification of ERK Signaling Complexes Using the Streptavidin-Binding Peptide (SBP) TagLiu Yang and Alexey Veraksa9. High-Throughput In Vitro Identification of Direct MAPK\/Erk SubstratesRona Grossman and Ze'ev Paroush10. Global Identification of ERK Substrates by Phosphoproteomics Based on IMAC and 2D-DIGEHidetaka Kosako and Kou Motani11. Analysis of Ras\/ERK Compartmentalization by Subcellular FractionationLorena Agudo-Iba\u00f1ez, Piero Crespo, and Berta Casar12. Cell-Based Assays to Study ERK Pathway\/Caveolin1 InteractionsRaffaele Strippoli, Asier Echarri, Miguel Angel del Pozo13. The Nuclear Translocation of ERKDenise A. Berti and Rony Seger14. Visualization of RAS\/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA)Zijian Tang and Chengkai Dai15. Measuring ERK Activity Dynamics in Single Living Cells Using FRET BiosensorsYannick Blum, Rafael D. Fritz, Hyunryul Ryu, and Olivier Pertz16. Quantifying Tensile Force and ERK Phosphorylation on Actin Stress FibersHiroaki Hirata, Mukund Gupta, Sri Ram Krishna Vedula, Chwee Teck Lim, Benoit Ladoux, and Masahiro Sokabe17. Co-Culture Activation of MAP Kinase in Drosophila S2 CellsJosefa Steinhauer18. Isolation of Mouse Embryonic Stem Cell Lines in the Study of ERK1\/2 MAP Kinase SignalingMarc K. Saba-El-Leil, Christophe Fr\u00e9min, and Sylvain Meloche19. 3D Organotypic Culture Model to Study Components of ERK SignalingAthina-Myrto Chioni, Rabia Tayba Bajwa, and Richard Grose20. Genetic Validation of Cell Proliferation via Ras-Independent Activation of the Raf\/Mek\/Erk PathwayCarmen G. Lechuga, Luc\u00eda Sim\u00f3n-Carrasco, Harrys K.C. Jacob, and Matthias Drosten21. Genome-Wide Analysis of RAS\/ERK Signaling TargetsJoshua P. Plotnik and Peter C. Hollenhorst22. Probing Chromatin Modifications in Response to ERK SignalingOzgur Oksuz and Wee-Wei Tee23. Analyzing pERK Activation during Planarian RegenerationSusanna Fraguas, Yoshihiko Umesono, Kiyokazu Agata, and Francesc Cebri\u00e024. Discovering Functional ERK Substrates Regulating Caenorhabditis elegans Germline DevelopmentJessica Jie Chen and Swathi Arur25. Reconstructing ERK Signaling in the Drosophila Embryo from Fixed ImagesBomyi Lim, Carmeline J. Dsilva, Ioannis G. Kevrekidis, and Stanislav Y. Shvartsman26. DrosophilaMarta For\u00e9s, Aikaterini Papagianni, Laura Rodr\u00edguez-Mu\u00f1oz, and Gerardo Jim\u00e9nez27. Analyzing ERK Signal Dynamics during Zebrafish SomitogenesisTakaaki Matsui and Yasumasa Bessho28. Modeling RASopathies with Genetically Modified Mouse ModelsIsabel Hern\u00e1ndez-Porrasand Carmen Guerra29. Dissecting Cell-Fate Determination through Integrated Mathematical Modeling of the ERK\/MAPK Signaling PathwaySung-Young Shin and Lan K. Nguyen","merchants_number":2,"ean":9781493964222,"category_id":103,"size":null,"min_price":118,"low_price_merchant_id":27291482,"ID":4909061,"merchants":["weltbild","euniverse"],"brand":"undefined","slug":"erk-signaling","url":"\/unterhaltung\/produkt\/erk-signaling\/","low_price_merchant_name":"Weltbild"}
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Leitfaden der Immunologie
1 Grundlagen der Immunologie.- I. Angeborene Immunität.- Schutzmechanismen gegen Infektionen.- Phagozytierende Zellen töten Mikroorganismen.- Komplement erleichtert die Phagozytose.- Komplement-vermittelte akut-entzündliche Reaktionen.- Humorale Mechanismen vermitteln eine zweite Abwehrstrategie.- Akute-Phase-Proteine.- Extrazelluläre Tötungsmechanismen.- 2 Grundlagen der Immunologie.... zur Produkt-Seite
5494793 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTIyMDkyNTYyX3hOQVdZUS1wbmc=!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTIyMDkyNTYyX3hOQVdZUS1wbmd8fnxodHRwczovL29zMS5tZWluZWNsb3VkLmlvL2IxMDE1OC9tZWRpYS9pbWFnZS8zYy85Yi9hNS8wNDczNjIyODAwMDAxQV82MDB4NjAwLmpwZ3x+fGh0dHBzOi8vYXNzZXRzLnRoYWxpYS5tZWRpYS9pbWcvYXJ0aWtlbC8xZjQ5MGQ4OWU4OTQxYjg5ZTFkMmI4ZmQ5OTBiNWE2ZjlhOWRiNGNmLTAwLTAwLmpwZWc=","post_title":"Leitfaden der Immunologie","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=24446219469&a=401125&m=11816&pref1=9783798506657","labels":[],"brand_id":1,"post_content":"1 Grundlagen der Immunologie.- I. Angeborene Immunit\u00e4t.- Schutzmechanismen gegen Infektionen.- Phagozytierende Zellen t\u00f6ten Mikroorganismen.- Komplement erleichtert die Phagozytose.- Komplement-vermittelte akut-entz\u00fcndliche Reaktionen.- Humorale Mechanismen vermitteln eine zweite Abwehrstrategie.- Akute-Phase-Proteine.- Extrazellul\u00e4re T\u00f6tungsmechanismen.- 2 Grundlagen der Immunologie.- II. Erworbene spezifische Immunit\u00e4t.- Die Notwendigkeit spezifischer Immunmechanismen.- Der Antik\u00f6rper - ein spezifischer Adapter.- Zellul\u00e4re Grundlagen der Antik\u00f6rperproduktion.- Erworbenes Ged\u00e4chtnis.- Die Spezifit\u00e4t der erworbenen Immunit\u00e4t.- Impfung.- Zellvermittelte Immunit\u00e4t sch\u00fctzt vor intrazellul\u00e4ren Organismen.- Immunpathologie.- Zusammenfassung.- 3 Antigen-erkennende Molek\u00fcle.- Die Immunglobuline.- Die Grundstruktur ist eine Einheit aus vier Peptiden.- Die Sequenzanalyse der Aminos\u00e4uren enth\u00fcllt Unterschiede in der Struktur der Immunglobuline.- Immunglobuline sind in Form globul\u00e4rer Dom\u00e4nen gefaltet, die unterschiedlichen Aufgaben dienen.- Immunglobulinklassen und Subklassen.- Der Haupt-Histokompatibilit\u00e4tskomplex (MHC).- Klasse-I- und Klasse-II-Molek\u00fcle sind Membran-gebundene Heterodimere.- Genkarte des Haupt-Histokompatibilit\u00e4tskomplexes.- Die Gene des MHC weisen einen bemerkenswerten Polymorphismus auf.- Vererbung des MHC.- Die Verteilung der MHC-Molek\u00fcle in den Geweben.- MHC-Funktionen.- Der T-Zellrezeptor.- Die Entstehung von Vielfalt in der Antigenerkennung.- Eine Vielzahl von Gensegmenten kodiert das Antik\u00f6rpermolek\u00fcl.- Ein \u00e4hnliches Genmuster kodiert den T-Zellrezeptor.- Mechanismen, die aus einem begrenzten Genpool enorme Diversit\u00e4t erzeugen.- Zusammenfassung.- 4 Antigenerkennung.- I. Prim\u00e4re Wechselwirkung.- Was ist ein Antigen?.- \u00dcber Epitope und Antigendeterminanten.- Antigene und Antik\u00f6rper interagieren aufgrund r\u00e4umlicher Komplementarit\u00e4t und nicht durch kovalente Bindung.- Die Kr\u00e4fte, die Antigene an Antik\u00f6rper binden, wachsen, wenn die Entfernung zwischen den Molek\u00fclen sich verringert.- Die Affinit\u00e4t oder Bindungsst\u00e4rke zwischen Antigen und Antik\u00f6rper.- Avidit\u00e4t zwischen Antiserum und Antigen - ein \"Bonus\"-Effekt der Multivalenz.- Die Spezifit\u00e4t der Antigenerkennung durch Antik\u00f6rper ist nicht absolut.- Was die T-Zelle \"sieht\".- Mit der Antigenit\u00e4t zusammenh\u00e4ngende Besonderheiten.- Zusammenfassung.- 5 Antigenerkennung.- II. Nachweismethoden und praktische Anwendung.- Pr\u00e4zipitation.- Agglutination durch Antik\u00f6rper.- Reinigung von Antigenen und Antik\u00f6rpern mittels Affinit\u00e4tschromatographie.- Immunologische Tests (Immunoassays) zum Nachweis von Antigenen und Antik\u00f6rpern mit markierten Reagenzien.- Der Immunoblot (Western Blot).- Die Immunhistochemie - eine Methode zur Lokalisierung von Antigenen in Zellen und Geweben.- Techniken zur Auftrennung von Zellen.- Neutralisation biologischer Aktivit\u00e4t.- Zusammenfassung.- 6 Die erworbene Immunantwort.- I. Vorg\u00e4nge nach der Antigenerkennung.- Wo geschieht das alles? Die Anatomie der Immunantwort.- Der Lymphknoten.- Milz.- Das sekretorische Immunsystem.- Das Knochenmark - ein wesentlicher Ort der Antik\u00f6rper-Synthese.- Antigen, quo vadis?.- Die Aktivierung von T-Zellen.- Oberfl\u00e4chenmarker immunkompetenter T- und B-Lymphozyten.- Die Aktivierung von T-Zellen erfordert zwei Signale.- Die Aktivierung von B-Zellen.- B-Zellen verm\u00f6gen auf drei unterschiedliche Typen von Antigenen zu reagieren.- Mechanismen der B-Zellaktivierung.- Klonale Expansion wird durch l\u00f6sliche T-Zell-faktoren erreicht.- Weitere T-Zellfaktoren leiten die Reifung fier Effektorzellen ein.- Zusammenfassung.- 7 Die erworbene Immunantwort.- II. Effektormechanismen.- Die Antik\u00f6rpersynthese.- Nachweis und zahlenm\u00e4\u00dfige Erfassung Antik\u00f6rper-bildender Zellen.- Protein-Synthese.- Die Umschaltung der Immunglobulinklassen erfolgt in den individuellen B-Zellen.- Ist die Spezifit\u00e4t der von den Folgegenerationen sezernierten Antik\u00f6rper die gleiche wie die der Immunglobuline","merchants_number":3,"ean":9783798506657,"category_id":103,"size":null,"min_price":71.9500000000000028421709430404007434844970703125,"low_price_merchant_id":1087639,"ID":5494793,"merchants":["dodax","euniverse","orell-fuessli"],"brand":"undefined","slug":"leitfaden-der-immunologie","url":"\/unterhaltung\/produkt\/leitfaden-der-immunologie\/","low_price_merchant_name":null}
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Vaccines for Invasive Fungal Infections
Part I: Discovery and Testing of Vaccine Candidates 1. Mouse Immunization with Radioattenuated Yeast Cells of Paracoccidioides brasiliensis Estefânia Mara do Nascimento Martins and Antero Silva Ribeiro de Andrade 2. Heat-Killed Yeast as a Pan-Fungal Vaccine Marife Martinez, Karl V. Clemons, and David A. Stevens 3. Immunoinformatics as a Tool for New Antifungal Va... zur Produkt-Seite
4908779 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNTIvYzkvNDgvNjQ4OTQzNzgwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNTIvYzkvNDgvNjQ4OTQzNzgwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC92YWNjaW5lcy1mb3ItaW52YXNpdmUtZnVuZ2FsLWluZmVjdGlvbnMtMjczNTQ1ODUzLmpwZw==","post_title":"Vaccines for Invasive Fungal Infections","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781493971039&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F377968%2Fvaccines-for-invasive-fungal-infections-methods-and-protocols%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Part I: Discovery and Testing of Vaccine Candidates\u00a01. Mouse Immunization with Radioattenuated Yeast Cells of Paracoccidioides brasiliensis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Estef\u00e2nia Mara do Nascimento Martins and Antero Silva Ribeiro de Andrade\u00a02. Heat-Killed Yeast as a Pan-Fungal Vaccine\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Marife Martinez, Karl V. Clemons, and David A. Stevens\u00a03. Immunoinformatics as a Tool for New Antifungal Vaccines\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Rupanjali Chaudhuri and Srinivasan Ramachandran\u00a04. Rational Design of T Lymphocyte Epitope-Based Vaccines Against Coccidioides Infection\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Brady J. Hurtgen and Chiung-Yu Hung\u00a05. Identification of Fungal T Cell Epitopes by Mass Spectrometry-Based Proteomics\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Bernd Roschitzki and Salom\u00e9 LeibundGut-Landmann\u00a06. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Shanjana Awasthi\u00a07. DNAhsp65 Vaccine as Therapy Against Paracoccidioidomycosis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Alice M. Ribeiro, Andr\u00e9 C. Amaral, Maria Sueli S. Felipe, and Anamelia L. Bocca\u00a08. Idiotypic Antifungal Vaccination: Immunoprotection by Antiidiotypic Antibiotic Antibodies\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Luciano Polonelli, Walter Magliani, and Stefania Conti\u00a09. Peptide Vaccine Against Paracoccidioidomycosis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Carlos P. Taborda and Luiz R. Travassos\u00a010. Methodology for Anti-Cryptococcal Vaccine Development\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ashok K. Chaturvedi and Floyd L. Wormley Jr.\u00a0Part II: Design and Delivery\u00a011. Beta-Glucan Particles as Vaccine Adjuvant Carriers\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Zeynep Mirza, Ernesto R. Soto, Fusun Dikengil, Stuart M. Levitz, and Gary R. Ostroff\u00a012. Th1-Inducing Agents in Prophylaxis and Therapy for Paracoccidioidomycosis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Thiago Aparecido da Silva, Fabr\u00edcio Freitas Fernandes, Taise Natali Landgraf, Adem\u00edlson Panunto-Castelo, and Maria Cristina Roque-Barreira\u00a013. Nanoparticle-Based Mycosis Vaccine\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Swaleha Zubair, Asim Azhar, Nazoora Khan, Ejaj Ahmad, Mohd Ajmal, and Owais Mohammad\u00a014. Yeast Expressing Gp43 Protein as a Vaccine Against Paracoccidioides brasiliensis Infection\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Aline Ferreira Oliveira and Paulo S.R. Coelho\u00a015. Vaccination with Phage-Displayed Antigenic Epitope\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Yicun Wang and Li Wang\u00a016. Preparation of an Oral Vaccine by Proteome Analysis and Molecular Display Technology\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Seiji Shibasaki and Mitsuyoshi Ueda\u00a0Part III: Endpoint Assessment\u00a017. Precise and Efficient In-Frame Integration of an Exogenous GFP Tag in Aspergillus fumigatus by a CRISPR System\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Chi Zhang and Ling Lu\u00a018. Endpoint Assessment in Rabbit Models of Invasive Pulmonary Aspergillosis and Mucormycosis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Vidmantas Petraitis, Ruta Petraitiene, William Hope, and Thomas J. Walsh\u00a0Part IV: Mechanism of Vaccine Protection\u00a019. CD4+ T Cells Mediate Aspergillosis Vaccine Protection\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Diana Diaz-Arevalo and Markus Kalkum\u00a020. T-Cell-Mediated Cross-Protective Immunity\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Nina Khanna and Claudia Stuehler\u00a021. Assessment of Post-Vaccination Phagocytic Activation Using Candida albicans Killing Assays\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Wenqing Li and Yan Hu\u00a022. Immunization with Antigen-Pulsed Dendritic Cells Against Highly Virulent Cryptococcus gattii Infection: Analysis of Cytokine-Producing T Cells\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Keigo Ueno, Makoto Urai, Shogo Takatsuka, Masahiro Abe, Yoshitsugu Miyazaki, and Yuki Kinjo\u00a0Part V: Translation to Clinical Use\u00a023. Testing Antifungal Vaccines in an Animal Model of Invasive Candidiasis and in Human Mucosal Candidiasis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Esther Segal","merchants_number":2,"ean":9781493971039,"category_id":103,"size":null,"min_price":168,"low_price_merchant_id":70255345,"ID":4908779,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"vaccines-for-invasive-fungal-infections","url":"\/unterhaltung\/produkt\/vaccines-for-invasive-fungal-infections\/","low_price_merchant_name":"eUniverse"}
Produkt merken zur Merkliste CHF 239.00
Multi-Target Drug Design Using Chem-Bioinformatic Approaches
Part I: Chem-Bioinformatic Tools 1. Cheminformatics Approaches to Study Drug Polypharmacology J. Jesús Naveja, Fernanda I. Saldívar-González, Norberto Sánchez-Cruz, and José L. Medina-Franco 2. Computational Predictions for Multi-Target Drug Design Neelima Gupta, Prateek Pandya, and Seema Verma 3. Computational Multi-Target Drug Design Azizeh Abdolmale... zur Produkt-Seite
4795472 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvYjUvNjMvMmMvNzA2NTExOTMwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvYjUvNjMvMmMvNzA2NTExOTMwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9tdWx0aS10YXJnZXQtZHJ1Zy1kZXNpZ24tdXNpbmctY2hlbS1iaW9pbmZvcm1hdGljLTI3ODE0MjcwMC5qcGc=","post_title":"Multi-Target Drug Design Using Chem-Bioinformatic Approaches","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781493987320&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F378741%2Fmulti-target-drug-design-using-chem-bioinformatic-approaches%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Part I: Chem-Bioinformatic Tools\u00a01. Cheminformatics Approaches to Study Drug Polypharmacology\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 J. Jes\u00fas Naveja, Fernanda I. Sald\u00edvar-Gonz\u00e1lez, Norberto S\u00e1nchez-Cruz, and Jos\u00e9 L. Medina-Franco\u00a02. Computational Predictions for Multi-Target Drug Design\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Neelima Gupta, Prateek Pandya, and Seema Verma\u00a03. Computational Multi-Target Drug Design\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Azizeh Abdolmaleki, Fereshteh Shiri, and Jahan Ghasemi\u00a0Part II: Computational Multi-Target Drug Design: Literature Reviews\u00a04. Multi-Target Drug Design for Neurodegenerative Diseases\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Marco Catto, Daniela Trisciuzzi, Domenico Alberga, Giuseppe Felice Mangiatordi, and Orazio Nicolotti\u00a05. Molecular Docking Studies in Multi-Target Antitubercular Drug Discovery\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 J\u00e9ssika de Oliveira Viana, Marcus T. Scotti, and Luciana Scotti\u00a06. Advanced Chemometric Modeling Approaches for the Design of Multi-Target Drugs against Neurodegenerative Diseases\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Amit Kumar Halder, Ana S. Moura, and M. Nata lia Dias Soeiro Cordeiro\u00a07. Computational Studies on Natural Products for the Development of Multi-Target Drugs\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Veronika Temml and Daniela Schuster\u00a08. Computational Design of Multi-Target Drugs against Alzheimer's Disease\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Sotirios Katsamakas and Dimitra Hadjipavlou-Litina\u00a09. Design of Multi-Target Directed Ligands as a Modern Approach for the Development of Innovative Drug Candidates for Alzheimer's Disease\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Vanessa Silva Gontijo, Fl\u00e1via Pereira Dias Viegas, Kris Simone Tranches Dias, and Claudio Viegas Jr.\u00a0Part III: Case Studies\u00a010. Virtual Screening for Dual Hsp90\/B-Raf Inhibitors\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Andrew Anighoro, Luca Pinzi, Giulio Rastelli, and J\u00fcrgen Bajorath\u00a011. Strategies for Multi-Target Directed Ligands: Application in Alzheimer's Disease (AD) Therapeutics\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Sucharita Das and Soumalee Basu\u00a012. Computational Design of Multi-Target Kinase Inhibitors\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Sinoy Sugunan and Rajanikant G.K.\u00a013. Proteochemometrics for the Prediction of Peptide Binding to Multiple HLA Class II Proteins\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ivan Dimitrov, Ventsislav Yordanov, Darren R. Flower, and Irini Doytchinova\u00a014. Linked Open Data: Ligand-Transporter Interaction Profiling and Beyond\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Stefanie Kickinger, Eva Hellsberg, Sankalp Jain, and Gerhard F. Ecker\u00a015. Design of Novel Dual Target Hits against Malaria and Tuberculosis Using Computational Docking\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Manoj Kumar and Anuj Sharma\u00a016. Computational Design of Multi-Target Drugs against Breast Cancer\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Shubhandra Tripathi, Gaurava Srivastava, and Ashok Sharma\u00a017. Computational Methods for Multi-Target Drug Designing against Mycobacterium tuberculosis\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Gaurava Srivastava, Ashish Tiwari, and Ashok Sharma\u00a0Part IV: Databases and Web Servers\u00a018. Development of a Web-Server for Identification of Common Lead Molecules for Multiple Protein Targets\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Abhilash Jayaraj, Ruchika Bhat, Amita Pathak, Manpreet Singh, and B. Jayaram\u00a019. Computational Method for Prediction of Targets for Breast Cancer Using siRNAs Approach\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Atul Tyagi, Mukti N. Mishra, and Ashok Sharma\u00a0Part V: Special Topics\u00a020. Historeceptomics:\u00a0 Integrating a Drug's Multiple Targets (Polypharmacology) with Their Expression Pattern in Human Tissues\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Timothy Cardozo\u00a021. Networking of Smart Drugs: A Chem-Bioinformatic Approach to Cancer Treatment\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Kavindra Kumar Kesari, Qazi Mohammad Sajid Jamal, Mohd. Haris Siddiqui, andJamal Mohammad Arif","merchants_number":2,"ean":9781493987320,"category_id":103,"size":null,"min_price":239,"low_price_merchant_id":70255345,"ID":4795472,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"multi-target-drug-design-using-chem-bioinformatic-approaches","url":"\/unterhaltung\/produkt\/multi-target-drug-design-using-chem-bioinformatic-approaches\/","low_price_merchant_name":"eUniverse"}
Produkt merken zur Merkliste CHF 59.90
Fractals in Biology and Medicine
Preface: Summary of the Symposium.- The Significance of Fractals for Biology and Medicine. An Introduction and Summary.- Fractal Geometry and Biomedical Sciences7.- A Fractal's Lacunarity, and how it can be Tuned and Measured.- Spatial and Temporal Fractal Patterns in Cell and Molecular Biology.- Chaos, Noise and Biological Data.- Fractal Landscapes in Physiology & Medicine: Long-Rang... zur Produkt-Seite
4478327 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZGYvYWIvYTAvNDE2ODU1NjYwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZGYvYWIvYTAvNDE2ODU1NjYwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Fractals in Biology and Medicine","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9783034896528&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F434834%2Ffractals-in-biology-and-medicine%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Preface: Summary of the Symposium.- The Significance of Fractals for Biology and Medicine. An Introduction and Summary.- Fractal Geometry and Biomedical Sciences7.- A Fractal's Lacunarity, and how it can be Tuned and Measured.- Spatial and Temporal Fractal Patterns in Cell and Molecular Biology.- Chaos, Noise and Biological Data.- Fractal Landscapes in Physiology & Medicine: Long-Range Correlations in DNA Sequences and Heart Rate Intervals.- Fractals in Biological Design and Morphogenesis.- Design of Biological Organisms and Fractal Geometry.- Fractal and Non-Fractal Growth of Biological Cell Systems.- Evolutionary Meaning, Functions and Morphogenesis of Branching Structures in Biology.- Relationship Between the Branching Pattern of Airways and the Spatial Arrangement of Pulmonary Acini - A Re-Examination from a Fractal Point of View.- Multivariate Characterization of Blood Vessel Morphogenesis in the Avian Chorioallantoic Membrane (CAM): Cell Proliferation, Length Density and Fractal Dimension.- Phyllotaxis or Self-Similarity in Plant Morphogenesis.- Fractals in Molecular and Cell Biology.- Evolutionary Interplay Between Spontaneous Mutation and Selection: Aleatoric Contributions of Molecular Reaction Mechanisms.- Error Propagation Theory of Chemically Solid Phase Synthesized Oligonucleotides and DNA Sequences for Biomedical Application.- Fractional Relaxation Equations for Protein Dynamics.- Measuring Fractal Dimensions of Cell Contours: Practical Approaches and their Limitations.- Fractal Properties of Pericellular Membrane from Lymphocytes and Leukemic Cells.- Cellular Sociology: Parametrization of Spatial Relationships Based on Voronoi Diagram and Ulam Trees.- A Fractal Analysis of Morphological Differentiation of Spinal Cord Neurons in Cell Culture.- Fractal Dimensions and Dendritic Branching of Neurons in the Somatosensory Thalamus.- Fractal Structure and Metabolic Functions.- Organisms as Open Systems.- Transfer to and across Irregular Membranes Modelled by Fractal Geometry.- Scaling and Active Surface of Fractal Membranes.- Structure Formation in Excitable Media.- Colony Morphology of the Fungus Aspergillus Oryzae.- Estimation of the Correlation Dimension of All-Night Sleep EEG Data with a Personal Super Computer.- Fractals in Pathology.- Changes in Fractal Dimension of Trabecular Bone in Osteoporosis: A Preliminary Study.- Use of the Fractal Dimension to Characterize the Structure of Cancellous Bone in Radiographs of the Proximal Femur.- Distribution of Local-Connected Fractal Dimension and the Degree of Liver Fattiness from Ultrasound.- Fractal Dimension as a Characterisation Parameter of Premalignant and Malignant Epithelial Lesions of the Floor of the Mouth.- Modelling.- Modelling HIV\/AIDS Dynamics.- Morphological Diagnosis Turns from Gestalt to Geometry.- Fluorescence Recovery after Photobleaching Studied by Total Internal Reflection Microscopy: An Experimental System for Studies on Living Cells in Culture.- Anomalous Diffusion and Angle-Dependency in the Theory of Fluorescence Recovery after Photobleaching.- List of Speakers.- List of Participants.","merchants_number":1,"ean":9783034896528,"category_id":103,"size":null,"min_price":59.89999999999999857891452847979962825775146484375,"low_price_merchant_id":70255345,"ID":4478327,"merchants":["euniverse"],"brand":"undefined","slug":"fractals-in-biology-and-medicine","url":"\/unterhaltung\/produkt\/fractals-in-biology-and-medicine\/","low_price_merchant_name":"eUniverse"}
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Retinal Degenerations
Retinal Degenerations: Genetics, Progression, and Therapeutics - Table of Contents J Tombran-Tink and CJ Barnstable (eds) University of Missouri-Kansas City and Yale University School of Medicine 1. Living with Retinal Degeneration Coping with Retinitis Pigmentosa: A Patientís View Gordon Cousins and James Cape 2. Degenerative Diseases of the Retina Epidemiology of ARMD Early in th... zur Produkt-Seite
4909205 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvOWIvMzMvMjgvMjk0ODY3MjcwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvOWIvMzMvMjgvMjk0ODY3MjcwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Retinal Degenerations","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781588296207&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F428148%2Fretinal-degenerations-biology-diagnostics-and-therapeutics%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Retinal Degenerations: Genetics, Progression, and Therapeutics - Table of Contents J Tombran-Tink and CJ Barnstable (eds) University of Missouri-Kansas City and Yale University School of Medicine 1. Living with Retinal Degeneration Coping with Retinitis Pigmentosa: A Patient\u00eds View Gordon Cousins and James Cape 2. Degenerative Diseases of the Retina Epidemiology of ARMD Early in the 21st Century Jie Jin Wang, Paul Mitchell and Ronald Klein 3. Leber Congenital Amaurosis: Biology, Diagnostics, and Therapeutics Robert K. Koenekoop 4. Macular Degeneration. Aging Changes and Novel Therapies Peter E. Liggett and Alejandro J. Lavaque 5. Stargardt Disease: from gene discovery to therapy Rando Allikmets 6. X-Linked Juvenile Retinoschisis Bernhard H.F. Weber and Ulrich Kellner 7. Retinal Degeneration in Usher Syndrome David S. Williams 8. Mouse models of RP Bo Chang, Norman L. Hawes, Muriel T. Davisson, J.R. Heckenlively 9. Mechanisms underlying retinal degenerations The Impact of Diabetes on Neuronal, Glial and Vascular Cells of the Retina: Implications for the Pathogenesis of Diabetic Retinopathy Sylvia B. Smith 10. Statins and Age-Related Maculopathy Gerald McGwin Jr. and Cynthia Owsley 11. The role of Drusen in Macular Degeneration and New Methods of Quantification R. Theodore Smith and Umer F. Ahmad 12. RPE lipofuscin: Formation, Properties, and Relevance to Retinal Degeneration Janet R. Sparrow 13. Genetic Modifiers that Affect Phenotypic Expression of Retinal Diseases Malia M. Edwards, Dennis M. Maddox, Jungyeon Won, J\u00b8rgen K. Naggert and Patsy M. Nishina 14. X-linked retinal dystrophies and microtubular functions within the retina Alan Wright and Xinhua Shu 15. Synaptic Remodeling in RetinalDegeneration You-Wei Peng and Fulton Wong 16. Developing Therapeutic Strategies for Retinal Degenerative Diseases On The Suppression of Photoreceptor Cell Death in Retinitis Pigmentosa Fiona Kernan, Alex G. McKee, G. J. Farrar and Peter Humphries 17. Cell-based therapies to restrict to progress of photoreceptor degeneration Raymond D. Lund and Shaomei Wang 18. Current Status of IPE Transplantation and its Potential as a Cell-Based Therapy for Age-Related Macular Degeneration and Retinal Dystrophies Makoto Tamai 19. Recent results in Retinal Transplantation give hope for restoring vision Robert B. Aramant, Norman D. Radtke and Magdalene J. Seiler 20. Stem Cells and Retinal Transplantation Joanne Yau, Henry Klassen, Tasneem Zahir and Michael Young 21. Application of Encapsulated Cell Technology for Retinal Degenerative Diseases Weng Tao and Rong Wen 22. Effective treatment for the canine RPE65 null mutation, a hereditary retinal dystrophy comparable to human Leber\u00eds Congenital Amaurosis Kristina Narfstr m, Gregory E. Tullis and Mathias Seeliger 23. The Use of Neuroprotective Factors in Retinal Degenerations Joyce Tombran-Tink and Colin Barnstable 24. Carbonic anhydrase inhibitors as a possible therapy for RP17, an Autosomal Dominant Retinitis Pigmentosa associated with the R14W mutation, apoptosis, and the unfolded protein response. George Rebello, Jacquie Greenberg and Raj Ramesar","merchants_number":1,"ean":9781588296207,"category_id":103,"size":null,"min_price":259,"low_price_merchant_id":70255345,"ID":4909205,"merchants":["euniverse"],"brand":"undefined","slug":"retinal-degenerations","url":"\/unterhaltung\/produkt\/retinal-degenerations\/","low_price_merchant_name":"eUniverse"}
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Selenium
Part I. The machinery of selenoprotein biosynthesis.- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis.- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro.- 3 Probing selenoprotein translation by ribosome profiling.- 4 Pathways in de novo biosynthesis of selenocysteine and c... zur Produkt-Seite
4882232 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNjcvN2YvOWMvNTgwNTY4MDgwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvNjcvN2YvOWMvNTgwNTY4MDgwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9zZWxlbml1bS0xNTc1NTkzMzEuanBn","post_title":"Selenium","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9783319412818&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F450206%2Fselenium-its-molecular-biology-and-role-in-human-health%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Part I. The machinery of selenoprotein biosynthesis.- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis.- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro.- 3 Probing selenoprotein translation by ribosome profiling.- 4 Pathways in de novo biosynthesis of selenocysteine and cysteine in eukaryotes.- 5 Prokaryotic selenoprotein biosynthesis and function.- 6 The role of selenium in human evolution.- 7 The chemistry of selenocysteine in proteins.- 8 Evolution of selenophosphate synthetase.- 9 Structure and mechanism of selenocysteine synthases.- 10 Mechanism, structure, and biological role of selenocysteine lyase.- Part II. Selenoproteins, their occurrence and function.- 11 Eukaryotic selenoproteomes.- 12 Prokaryotic selenoproteins and selenoproteomes.- 13 Functional genomics of selenoproteins and Se-responsive pathways.- 14 Selenium regulation of the selenoprotein and non-selenoprotein transcriptomes in a variety of species.- 15 77Se NMR spectroscopy of selenoproteins.- 16 Thioredoxin reductase 1 as an anticancer drug target.- 17 Basics and news on glutathione peroxidases.- 18 Glutathione Peroxidase 4.- 19 The 15 kDa Selenoprotein: Insights into its regulation and function.- 20 Selenoprotein K and protein palmitoylation in regulating immune cell functions.- 21 Selenoprotein M: Structure, expression and functional relevance.- 22 Selenoprotein P and selenium distribution in mammals.- 23 Selenoprotein T: From discovery to functional studies using conditional knockout mice.- 24 Biochemistry and function of methionine sulfoxide reductase.- Part III. Dietary selenium and its impact on human health.- 25 Selenium: Dietary sources, human nutritional requirements and intake across populations.- 26 Human clinical trials involving selenium.- 27 Status of dietary selenium in cancer prevention.- 28 Selenium in HIV\/AIDS.- 29 Genetic variations in the genes for selenoproteins implicate the encoded proteins in cancer etiology.- 30 Is adequate selenium important for healthy human pregnancy?.- 31 The epidemiology of selenium and human health.- 32 Sex-specific differences in biological effects and metabolism of selenium.- 33 Selenium and endocrine tissues.- 34 Selenium antagonism with mercury and arsenic: from chemistry to population health and demography.- 35 Biological selenium species and selenium speciation in biological samples.- 36 Selenoproteins in nervous system development, function and degeneration.- 37 Interplay of selenoproteins and different antioxidant systems in various cancers.- 38 Glutathione peroxidase 2, a selenoprotein exhibiting a dual personality in preventing and promoting cancer.- 39 Selenoproteins in cardiovascular redox pathology.- 40 What do we know about selenium contributions to muscle physiology?.- 41 Tissue-specific regulation of thyroid status by selenodeiodinases.- 42 The role of selenoproteins in resolution of inflammation.- 43 Glutathione peroxidase 4 and ferroptosis.- 44 Mutations in humans that adversely affect the selenoprotein synthesis pathway.- 45 Alteration of selenoprotein expression during stress and in aging.- Part V. Biological models for elucidating the role of selenium and selenoproteins in biology and medicine.- 46 Selenocysteine tRNA[Ser]Sec mouse models for elucidating roles of selenoproteins in health and development.- 47 Mouse models that target individual selenoproteins.- 48 The naked mole rat and selenium.- 49 Glutathione peroxidase 1: Models for diabetes and obesity.- 50 Selenium in livestock and other domestic animals","merchants_number":2,"ean":9783319412818,"category_id":103,"size":null,"min_price":211,"low_price_merchant_id":70255345,"ID":4882232,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"selenium-1","url":"\/unterhaltung\/produkt\/selenium-1\/","low_price_merchant_name":"eUniverse"}
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Epitope Mapping Protocols
Section I: B-cell Epitope Mapping 1. What Is a B Cell Epitope? Marc H. V. Van Regenmortel Subsection A: Whole Antigen Methods 2. Structural Basis of Antibody-Antigen Interactions Eric J. Sundberg 3. Epitope Mapping of Antibody-Antigen Complexes by Nuclear Magnetic Resonance Spectroscopy Osnat Rosen and Jacob Anglister 4. A Solid-Phase Mutual Inhibition Assay with Labeled Antigen Masah... zur Produkt-Seite
4051532 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMGIvZDcvODUvMjk5MjE1NTEwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMGIvZDcvODUvMjk5MjE1NTEwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2M0LXN0YXRpYy5kb2RheC5jb20vdjIvMTgwLTE4MC0xMjE5NzU1NTlfcGFHeFhuLXBuZw==","post_title":"Epitope Mapping Protocols","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781934115176&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F382838%2Fepitope-mapping-protocols%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Section I: B-cell Epitope Mapping 1. What Is a B Cell Epitope? Marc H. V. Van Regenmortel Subsection A: Whole Antigen Methods 2. Structural Basis of Antibody-Antigen Interactions Eric J. Sundberg 3. Epitope Mapping of Antibody-Antigen Complexes by Nuclear Magnetic Resonance Spectroscopy Osnat Rosen and Jacob Anglister 4. A Solid-Phase Mutual Inhibition Assay with Labeled Antigen Masahide Kuroki 5. Epitope Mapping by Surface Plasmon Resonance P\u00e4r S\u00e4fsten 6. Proteolytic Fragmentation for Epitope Mapping Maria R. Mazzoni, Francesca Porchia, and Heidi E. Hamm 7. Epitope Mapping by Proteolysis of Antigen-Antibody Complexes Suraj Dhungana, Jason G. Williams, Michael B. Fessler, and Kenneth B. Tomer 8. Identifying Residues in Antigenic Determinants by Chemical Modification Howard M. Reisner and Roger L. Lundblad 9. Epitope Mapping by Differential Chemical Modification of Antigens Suraj Dhungana, Michael B. Fessler, and Kenneth B. Tomer Subsection B: Peptide Library Approaches 10. Linear B-Cell Epitope Mapping Using Enzyme-Linked Immunosorbent Assay for Libraries of Overlapping Synthetic Peptides Michael W. Heuzenroeder, Mary D. Barton, Thiru Vanniasinkam, and Tongted Phumoonna 11. Antibody Epitope Mapping Using SPOTTM Peptide Arrays Ulrich Reineke and Robert Sabat 12. Peptide Microarrays for Profiling of Modification State Specific Antibodies Johannes Zerweck, Antonia Masch, and Mike Schutkowski 13. Epitope Mapping Using Phage Display Peptide Libraries Volker B\u00f6ttger and Angelika B\u00f6ttger 14. Antibody Epitope Mapping Using De Novo Generated Synthetic Peptide Libraries Ulrich Reineke 15. Antibody Specificity Profiling on Functional Protein Microarrays Dawn R.Mattoon and Barry Schweitzer 16. Peptide Microarrays for Determination of Cross-Reactivity Alexandra Thiele Subsection C: Profiling of Antibody Signatures in Biological Fluids 17. Epitope Mapping Using Randomly Generated Peptide Libraries Juliane Bongartz, Nicole Bruni, and Michal Or-Guil 18. Probing the Epitope Signatures of IgG Antibodies in Human Serum from Patients With Autoimmune Disease Peter Lorenz, Michael Kreutzer, Johannes Zerweck, Mike Schutkowski, and Hans-J\u00fcrgen Thiesen 19. Microarrayed Allergen Molecules for Diagnostics of Allergy Jing Lin, Ludmilla Bardina, and Wayne G. Shreffler 20. Humoral Response to Immunoselected Phage-Displayed Peptides by Microarray-Based Method Lina Cekaite, Eiving Hovig, and Mouldy Sioud Subsection D: Antigen Expressed from Recombinant DNA 21. Epitope Mapping Using Homolog-Scanning Mutagenesis Lin-Fa Wang 22. Epitope Mapping by Region-Specified PCR-Mutagenesis Tsutomu Mikawa, Masayuki lkeda, and Takehiko Shibata 23. Epitope Mapping Using Phage-Display Random Fragment Libraries Lin-Fa Wang and Meng Yu Subsection E: B-Cell Epitope Prediction 24. Prediction of Linear B-cell Epitopes Ulf Reimer Section II: T-Cell Epitope Mapping 25. Molecular Recognition of Diverse Ligands by T Cell Receptors Eric J. Sundberg 26. Identification of Human MHC Class I Binding Peptides using the iTOPIATM Epitope Discovery System Markus Wulf, Petra Hoehn, and Peter Trinder 27. T-Cell Epitope Mapping in Mycobacterium Tuberculosis Using PepMixes Created by Micro-Scale SPOTTM Synthesis Marisa Frieder and David M. Lewinsohn 28. High-Throughput T Cell Epitope Discovery Through MHC Peptide Exchange Sine Reker Hadrup, Mireille Toebes,","merchants_number":2,"ean":9781934115176,"category_id":103,"size":null,"min_price":143,"low_price_merchant_id":70255345,"ID":4051532,"merchants":["euniverse","dodax"],"brand":"undefined","slug":"epitope-mapping-protocols","url":"\/unterhaltung\/produkt\/epitope-mapping-protocols\/","low_price_merchant_name":"eUniverse"}
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Uremic Toxins
Parathyroid Hormone: A Uremic Toxin.- Retention Patterns.- Middle Molecules and the 7 C Factor.- Middle Molecules as a Marker of Uremic Toxins.- The Abiko Factor.- Polyamines and Uremia.- Roles of Hippurate and Indoxyl Sulfate in the Impaired Ligand Binding by Azotemic Plasma.- Hippuric Acid as a Marker.- Suppressive Effect of Quinolinic Acid and Hippuric Acid on Bone Marrow Erythroid... zur Produkt-Seite
4103129 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZGQvNTQvOGYvNDI5NDI2NTIwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvZGQvNTQvOGYvNDI5NDI2NTIwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Uremic Toxins","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781468454475&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fbiologie%2F371460%2Furemic-toxins%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Parathyroid Hormone: A Uremic Toxin.- Retention Patterns.- Middle Molecules and the 7 C Factor.- Middle Molecules as a Marker of Uremic Toxins.- The Abiko Factor.- Polyamines and Uremia.- Roles of Hippurate and Indoxyl Sulfate in the Impaired Ligand Binding by Azotemic Plasma.- Hippuric Acid as a Marker.- Suppressive Effect of Quinolinic Acid and Hippuric Acid on Bone Marrow Erythroid Growth and Lymphocyte Blast Formation in Uremia.- Purine Metabolites in Uraemia.- The Role of Lipids in Progressive Glomerular Disease.- Aluminum an Uremic Toxin.- The Insulin-Resistance Inducing Factor Associated with Uremia.- Pathogenesis and Consequences of the Alteration of Glucose Metabolism in Renal Insufficiency.- Separation of Peptidic Inhibitor of Erythropoiesis in Uremia.- Uremic Toxins Inhibit the Platelet Malonyldialdehyde Production Rate.- A Possible Regulatory System of Microtubule Formation Among Uremic Toxins.- Encephalopathic Toxicity: An Experimental Model of Uremia and Solute-Specific Dialysis.- Intellectual Impairment in Chronic Renal Failure.- The Fraction b 4-2: Isolation, Characterization and Biological Activities with Reference to Uremic Polyneuropathy.- Intracellular Acid-Base and Energy Metabolism in Uremia: A Preliminary Study of Five Patients Before and During Dialysis Treatment.- Is Selenium Deficiency the Cause of Uraemic Cardiomyopathy?.- Does Hypermagnesemia Suppress Parathyroid Activity and Therefore Play a Role in Amelioration of Uremic Toxicity?.- Synthesis and Structure-Activity Relationships of Thymopoietin.- The Immunosuppressive Fraction Isolated from Uremic Ultrafiltrates: Attempted Characterization of the Mechanism of Action.- Isolation of an Immunosuppressive Fraction from Uremic Ultrafiltrates.- Binding of Organic Acids to Surface Receptors of Lymphocytes as an Immunosuppressive Mechanism in Uremia.- Uremic Dysmetabolism and its Effect on Immunocompetent and Erythroid Cell Function.- Conversion of Ammonia to Glutamate by L-Glutamic Dehydrogenase, Alcohol Dehydrogenase and NAD+ Immunobilized within Lipid-Polyamide Polyethyleneimine Microcapsules.- A Purification Method by Uncoated Charcoal.- Amino Acid Composition of Uremic Middle and Low Molecular Weight Retention Products.- Biochemical Elucidation and HPLC Fractionation of Fluorescent Peptides in Patients with Chronic Renal Failure.- Separation from Uremic Body Fluids and Normal Urine of Na+, K+-ATPase Inhibitor.- Isolation of Sialylcompounds from Hemofiltrate of Chronic Uremic Patients and Identification by Nuclear Magnetic Resonance.- Identification of Two Uremic toxins by Nuclear Magnetic Resonance and Mass Spectrometry.- Kinetic of Solute Removal in Hemodialysis.- An Advanced, User-Friendly Microcomputer Program for Hemodialysis Kinetics.- Is Serum Urea a Good Index for Predicting Morbidity in Hemodialysis (HD)?.- Predicted time of Dialysis in Patients with Different Volumes of Urea Distribution-The Use of Mathematical Model.- Membranes and their Removal of Uremic Toxins.- Replacement of Excretory Kidney Function by High-Efficiency Hemodiafiltration (HDF) with a Peptide-Permeable Membrane.- Paired filtration-Dialysis (PFD): A Separate Convective-Diffusive System for Extracorporeal Blood Purification in Uraemic Patients.- Removal of Small Proteins-The Stepchild of Dialysis Therapy Protein Permeability of Different Hemofiltration Membranes Analysed by SDS-Poly-acrylamide Gel Electrophoresis (SDS-Page).- Hemofiltration-Induced Serum Modifications in the Pattern of Larger Molecules.- Carnitine Depletion During Chronic Hemodialysisi Effect of Substitution on Free Carnitine Plasma Levels.","merchants_number":1,"ean":9781468454475,"category_id":103,"size":null,"min_price":74.900000000000005684341886080801486968994140625,"low_price_merchant_id":70255345,"ID":4103129,"merchants":["euniverse"],"brand":"undefined","slug":"uremic-toxins","url":"\/unterhaltung\/produkt\/uremic-toxins\/","low_price_merchant_name":"eUniverse"}
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Rezepte für die Anabole Diät
Low Carb Diät-Rezepte Die besten Gerichte für die Anabole Diät Schneller Muskelzuwachs bei gleichzeitigem Fettabbau, und dabei jeden Tag satt essen - das geht mit der Anabolen Diät! Im gleichnamigen Buch sind die Grundzüge und Anwendung dieser Ernährung beschrieben. Im ersten Teil des vorliegenden Buches ?Low Carb Rezepte für die Anabole Diät? wird dieses Ernährungskonzept wissenschaf... zur Produkt-Seite
4698781 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvcmV6ZXB0ZS1mdWVyLWRpZS1hbmFib2xlLWRpYWV0LTM2OTg2NjA1MS5qcGc=!aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvcmV6ZXB0ZS1mdWVyLWRpZS1hbmFib2xlLWRpYWV0LTM2OTg2NjA1MS5qcGd8fnw=","post_title":"Rezepte f\u00fcr die Anabole Di\u00e4t","deeplink":"https:\/\/track.adtraction.com\/t\/t?a=1632201226&as=1592767275&t=2&tk=1&url=https:\/\/www.weltbild.ch\/artikel\/x\/_14689650-1","labels":[],"brand_id":1,"post_content":"Low Carb Di\u00e4t-Rezepte Die besten Gerichte f\u00fcr die Anabole Di\u00e4t Schneller Muskelzuwachs bei gleichzeitigem Fettabbau, und dabei jeden Tag satt essen - das geht mit der Anabolen Di\u00e4t! Im gleichnamigen Buch sind die Grundz\u00fcge und Anwendung dieser Ern\u00e4hrung beschrieben. Im ersten Teil des vorliegenden Buches ?Low Carb Rezepte f\u00fcr die Anabole Di\u00e4t? wird dieses Ern\u00e4hrungskonzept wissenschaftlich untermauert und weiter verfeinert. Nicht nur der Reduzierung der Kohlenhydratzufuhr, sondern auch der Versorgung mit den korrekten Fetts\u00e4uren muss verst\u00e4rkte Aufmerksamkeit gewidmet werden. Nur so lassen sich die Vorteile der ?Anabolen Di\u00e4t?; wie deutlicher Fettabbau, gesteigerte sportliche Leistungsf\u00e4higkeit und optimale Gesundheit, voll aussch\u00f6pfen. Wer bislang der anabolen Di\u00e4t wegen vermeintlich ?gesundheitlicher Nachteile? nichts abgewinnen konnte, wird \u00fcberrascht sein, zu erfahren, dass es unseren fr\u00fchen Vorfahren nur dank einer solchen Ern\u00e4hrung \u00fcberhaupt m\u00f6glich war, sich zum modernen Menschen zu entwickeln. Der \u00dcbergang zum Getreideverzehr entsprang der reinen Not, nicht aber dem Wunsch, Brot statt Fleisch zu essen. Der Verzehr von Kohlenhydraten verursacht h\u00e4ufig nicht nur \u00dcbergewicht, sondern ist ? neben den bekannten Problemen wie Diabetes und Herz-Kreislauf-Erkrankungen ? auch f\u00fcr eine ganze Reihe weiterer, ernster Krankheiten verantwortlich. Getreideprodukten und H\u00fclsenfr\u00fcchten wird heute eine urs\u00e4chliche Rolle bei der Entstehung von Autoimmunkrankheiten wie Sprue, Morbus Chrohn und Multipler Sklerose zugesprochen; eine ganze Reihe weiterer Beschwerden (Migr\u00e4ne, Hautprobleme etc.) k\u00f6nnen durch Verzicht auf Getreideproteine gelindert, bzw. geheilt werden. Dar\u00fcber hinaus liefern die Fette in unserer Ern\u00e4hrung eben nicht nur Kalorien, sondern sie sind in vielf\u00e4ltiger Weise f\u00fcr die ordnungsgem\u00e4ssen Funktion des Organismus verantwortlich. Langj\u00e4hriger Verzehr der falschen Fette ist mittlerweile als eine der Hauptursachen f\u00fcr Zivilisationskrankheiten wie Herzerkrankungen und Krebs erkannt. Die korrekte Balance der Fetts\u00e4uren im Organismus wirkt sich dagegen nicht nur positiv in der Behandlung vieler Erkrankungen aus, sondern verhilft auch dem Sportler auf nat\u00fcrliche Weise zu einem anabolen Stoffwechsel und sportlichen H\u00f6chstleistungen. Im zweiten Teil des Buches wird auf die t\u00e4gliche Praxis mit der Anabolen Di\u00e4t eingegangen: Weshalb man sich nicht durch eine tiefe Ketose qu\u00e4len muss, um K\u00f6rperfett abzubauen, der Gesundheitscheck zu Beginn der ketogenen Ern\u00e4hrung, die verschiedenen Formen der kohlenhydratreduzierten Di\u00e4t und welche Lebensmittel f\u00fcr die Anabole Di\u00e4t am besten geeignet sind. Mit Hinweisen auf ?ketogenes Fast Food?; zu echten und vermeintlichen Vorteilen von Bio-Produkten, sowie zur Fetts\u00e4urenzusammenstellung erleichtern die t\u00e4gliche Durchf\u00fchrung der Anabolen Di\u00e4t. Im dritten Teil folgen die Rezepte f\u00fcr eine gesunde, ketogene Ern\u00e4hrung. Diese muss weder einseitig sein, noch fade schmecken: \u00dcber 100 Rezepte f\u00fcr Fleisch, Fisch und Meeresfr\u00fcchte, Eierspeisen, Suppen, Gem\u00fcse und Salate, sowie f\u00fcr Snacks, Sossen und Dips. \u00dcber einfache, schnell zubereitete Gerichte bis hin zu Feinschmecker-Mahlzeiten, warme oder kalte K\u00fcche ? aber immer arm an Kohlenhydraten. Alle Gerichte werden mit N\u00e4hrwertangaben (Kohlenhydrate, Protein, Fett, Broteinheiten pro Portion) pr\u00e4sentiert. Die Zubereitung der Mahlzeiten ist pr\u00e4zise beschrieben, so dass auch Laien sich mit diesem Kochbuch zurechtfinden. Mit vielen Tips und Tricks zur Praxis der ketogenen Ern\u00e4hrung, \u00fcbersichtlichen Tafeln und Tabellen, sowie einer F\u00fclle von Informationen zum optimalen Einsatz der Anabolen Di\u00e4t in allen Bereichen ? Sport, Gewichtsverlust und Rekonvaleszenz.","merchants_number":2,"ean":9783929002348,"category_id":103,"size":null,"min_price":27.89999999999999857891452847979962825775146484375,"low_price_merchant_id":27291482,"ID":4698781,"merchants":["weltbild","orell-fuessli"],"brand":"undefined","slug":"rezepte-fur-die-anabole-diat","url":"\/unterhaltung\/produkt\/rezepte-fur-die-anabole-diat\/","low_price_merchant_name":"Weltbild"}
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Selenium
Part I. The machinery of selenoprotein biosynthesis.- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis.- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro.- 3 Probing selenoprotein translation by ribosome profiling.- 4 Pathways in de novo biosynthesis of selenocysteine and c... zur Produkt-Seite
4887878 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMmYvZjUvMWQvNzI5MjEwMDIwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMmYvZjUvMWQvNzI5MjEwMDIwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9zZWxlbml1bS0yNjE2ODg4NDguanBn","post_title":"Selenium","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9783319823133&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F469536%2Fselenium-its-molecular-biology-and-role-in-human-health%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Part I. The machinery of selenoprotein biosynthesis.- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis.- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro.- 3 Probing selenoprotein translation by ribosome profiling.- 4 Pathways in de novo biosynthesis of selenocysteine and cysteine in eukaryotes.- 5 Prokaryotic selenoprotein biosynthesis and function.- 6 The role of selenium in human evolution.- 7 The chemistry of selenocysteine in proteins.- 8 Evolution of selenophosphate synthetase.- 9 Structure and mechanism of selenocysteine synthases.- 10 Mechanism, structure, and biological role of selenocysteine lyase.- Part II. Selenoproteins, their occurrence and function.- 11 Eukaryotic selenoproteomes.- 12 Prokaryotic selenoproteins and selenoproteomes.- 13 Functional genomics of selenoproteins and Se-responsive pathways.- 14 Selenium regulation of the selenoprotein and non-selenoprotein transcriptomes in a variety of species.- 15 77Se NMR spectroscopy of selenoproteins.- 16 Thioredoxin reductase 1 as an anticancer drug target.- 17 Basics and news on glutathione peroxidases.- 18 Glutathione Peroxidase 4.- 19 The 15 kDa Selenoprotein: Insights into its regulation and function.- 20 Selenoprotein K and protein palmitoylation in regulating immune cell functions.- 21 Selenoprotein M: Structure, expression and functional relevance.- 22 Selenoprotein P and selenium distribution in mammals.- 23 Selenoprotein T: From discovery to functional studies using conditional knockout mice.- 24 Biochemistry and function of methionine sulfoxide reductase.- Part III. Dietary selenium and its impact on human health.- 25 Selenium: Dietary sources, human nutritional requirements and intake across populations.- 26 Human clinical trials involving selenium.- 27 Status of dietary selenium in cancer prevention.- 28 Selenium in HIV\/AIDS.- 29 Genetic variations in the genes for selenoproteins implicate the encoded proteins in cancer etiology.- 30 Is adequate selenium important for healthy human pregnancy?.- 31 The epidemiology of selenium and human health.- 32 Sex-specific differences in biological effects and metabolism of selenium.- 33 Selenium and endocrine tissues.- 34 Selenium antagonism with mercury and arsenic: from chemistry to population health and demography.- 35 Biological selenium species and selenium speciation in biological samples.- 36 Selenoproteins in nervous system development, function and degeneration.- 37 Interplay of selenoproteins and different antioxidant systems in various cancers.- 38 Glutathione peroxidase 2, a selenoprotein exhibiting a dual personality in preventing and promoting cancer.- 39 Selenoproteins in cardiovascular redox pathology.- 40 What do we know about selenium contributions to muscle physiology?.- 41 Tissue-specific regulation of thyroid status by selenodeiodinases.- 42 The role of selenoproteins in resolution of inflammation.- 43 Glutathione peroxidase 4 and ferroptosis.- 44 Mutations in humans that adversely affect the selenoprotein synthesis pathway.- 45 Alteration of selenoprotein expression during stress and in aging.- Part V. Biological models for elucidating the role of selenium and selenoproteins in biology and medicine.- 46 Selenocysteine tRNA[Ser]Sec mouse models for elucidating roles of selenoproteins in health and development.- 47 Mouse models that target individual selenoproteins.- 48 The naked mole rat and selenium.- 49 Glutathione peroxidase 1: Models for diabetes and obesity.- 50 Selenium in livestock and other domestic animals","merchants_number":2,"ean":9783319823133,"category_id":103,"size":null,"min_price":211,"low_price_merchant_id":70255345,"ID":4887878,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"selenium-2","url":"\/unterhaltung\/produkt\/selenium-2\/","low_price_merchant_name":"eUniverse"}
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Characterization of Nanoparticles Intended for Drug Delivery
Preface Table of Contents... Contributing Authors... Part I Introduction 1. Evaluating Nanomedicines: Obstacles and Advancements Magdalena Swierczewska, Rachael M. Crist, and Scott E. McNeil Part II Sterility and Endotoxin Testing 2. Detection of Bacterial Contamination in Nanoparticle Formulations by Agar Plate Test Timothy M. Potter, Barry W. Neun, Anna N. Ilinskaya, and Marina A.... zur Produkt-Seite
4909145 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvYTcvYTAvYmIvNjQ4OTQ2MjMwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvYTcvYTAvYmIvNjQ4OTQ2MjMwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9jaGFyYWN0ZXJpemF0aW9uLW9mLW5hbm9wYXJ0aWNsZXMtaW50ZW5kZWQtZm9yLWRydWctMjczNTQ3NzI4LmpwZw==","post_title":"Characterization of Nanoparticles Intended for Drug Delivery","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781493973507&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F378044%2Fcharacterization-of-nanoparticles-intended-for-drug-delivery-methods-and-protocols%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Preface Table of Contents... Contributing Authors... Part I Introduction 1. Evaluating Nanomedicines: Obstacles and Advancements Magdalena Swierczewska, Rachael M. Crist, and Scott E. McNeil Part II Sterility and Endotoxin Testing 2. Detection of Bacterial Contamination in Nanoparticle Formulations by Agar Plate Test Timothy M. Potter, Barry W. Neun, Anna N. Ilinskaya, and Marina A. Dobrovolskaia 3. Considerations and Some Practical Solutions to Overcome Nanoparticle Interference with LAL Assays and to Avoid Endotoxin Contamination in Nanoformulations Barry W. Neun and Marina A. Dobrovolskaia Part III Physicochemical Characterization 4. Elemental Analysis in Biological Matrices Using ICP-MS Matthew N. Hansen and Jeffrey D. Clogston 5. PEG Quantitation Using Reversed Phase High Performance Liquid Chromatography and Charged Aerosol Detection Mackensie C. Smith and Jeffrey D. Clogston 6. Quantitation of Surface Coating on Nanoparticles Using Thermogravimetric Analysis Alpana A. Dongargaonkar and Jeffrey D. Clogston 7. Immunoelectron Microscopy for Visualization of Nanoparticles Sarah R. Anderson, David Parmiter, Ulrich Baxa, and Kunio Nagashima 8. Imaging of Liposomes by Transmission Electron Microscopy Ulrich Baxa Part IV Immunology 9. Updated Method for In Vitro Analysis of Nanoparticle Hemolytic Properties Barry W. Neun, Anna N. Ilinskaya, and Marina A. Dobrovolskaia 10. In Vitro Assessment of Nanoparticle Effects on Blood Coagulation Timothy M. Potter, Jamie C. Rodriguez, Barry W. Neun, Anna N. Ilinskaya, Edward Cedrone, and Marina A. Dobrovolskaia 11. In Vitro Analysis of Nanoparticle Effects on the Zymosan Uptake by Phagocytic Cells Timothy M. Potter, Sarah L. Skoczen, Jamie C. Rodriguez, Barry W. Neun, Anna N. Ilinskaya, Edward Cedrone, and Marina A. Dobrovolskaia 12. Assessing NLRP3 Inflammasome Activation by Nanoparticles Bhawna Sharma, Christopher B. McLeland, Timothy M. Potter, Stephan T. Stern, and Pavan P. Adiseshaiah 13. Analysis of Complement Activation by Nanoparticles Barry W. Neun, Anna A. Ilinskaya, and Marina A. Dobrovolskaia 14. Methods for Analysis of Nanoparticle Immunosuppressive Properties In Vitro and In Vivo Timothy M. Potter, Barry W. Neun, and Marina A. Dobrovolskaia 15. Analysis of Pro-Inflammatory Cytokine and Type II Interferon Induction by Nanoparticles Timothy M. Potter, Barry W. Neun, Jamie C. Rodriguez, Anna N. Ilinskaya, and Marina A. Dobrovolskaia 16. Analysis of Nanoparticle Adjuvant Properties In Vivo Barry W. Neun and Marina A. Dobrovolskaia 17. In Vitro and In Vivo Methods for Analysis of Nanoparticle Potential to Induce Delayed Type Hypersensitivity Reactions Timothy M. Potter, Barry W. Neun, and Marina A. Dobrovolskaia 18. Autophagy Monitoring Assay II: Imaging Autophagy Induction in LLC-PK1 Cells Using GFP-LC3 Protein Fusion Construct Pavan P. Adiseshaiah, Sarah L. Skoczen, Jamie C. Rodriguez, Timothy M. Potter, Krishna Kota, and Stephan T. Stern Part V Drug Release and In Vivo Efficacy 19. Improved Ultrafiltration Method to Measure Drug Release from Nanomedicines Utilizing a Stable Isotope Tracer Sarah L. Skoczen and Stephan T. Stern 20. Designing an In Vivo Efficacy Study of Nanomedicines for Preclinical Tumor Growth Inhibition Pavan P. Adiseshaiah and Stephan T. Stern","merchants_number":2,"ean":9781493973507,"category_id":103,"size":null,"min_price":157,"low_price_merchant_id":70255345,"ID":4909145,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"characterization-of-nanoparticles-intended-for-drug-delivery-1","url":"\/unterhaltung\/produkt\/characterization-of-nanoparticles-intended-for-drug-delivery-1\/","low_price_merchant_name":"eUniverse"}
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Phytoplasma
1. The Phytoplasmas - An IntroductionMatt Dickinson, Melanie Tuffen, and Jennifer Hodgetts2. Techniques for the Maintenance and Propagation of Phytoplasmas in Glasshouse Collections of Catharanthus roseusJennifer Hodgetts, David Crossley, and Matt Dickinson3. Micropropagation and Maintenance of Phytoplasmas in Tissue CultureAssunta Bertaccini, Samanta Paltrinieri, Marta Martini, Mara ... zur Produkt-Seite
4325939 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvcGh5dG9wbGFzbWEtMjczNTIxNDE5LmpwZw==!aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvcGh5dG9wbGFzbWEtMjczNTIxNDE5LmpwZ3x+fGh0dHBzOi8vb3MxLm1laW5lY2xvdWQuaW8vYjEwMTU4L21lZGlhL2ltYWdlLzRiLzQxL2Q0LzMzMzUxMDgwMDAwMDFBXzYwMHg2MDAuanBn","post_title":"Phytoplasma","deeplink":"https:\/\/track.adtraction.com\/t\/t?a=1632201226&as=1592767275&t=2&tk=1&url=https:\/\/www.weltbild.ch\/artikel\/x\/_17490608-1","labels":[],"brand_id":1,"post_content":"1. The Phytoplasmas - An IntroductionMatt Dickinson, Melanie Tuffen, and Jennifer Hodgetts2. Techniques for the Maintenance and Propagation of Phytoplasmas in Glasshouse Collections of Catharanthus roseusJennifer Hodgetts, David Crossley, and Matt Dickinson3. Micropropagation and Maintenance of Phytoplasmas in Tissue CultureAssunta Bertaccini, Samanta Paltrinieri, Marta Martini, Mara Tedeschi, and Nicoletta Contaldo4. Dodder Transmission of PhytoplasmasJaroslava Pribylov\u00e1 and Josef Spak5. Insect Maintenance and TransmissionHeather Kingdom6. Capturing Insect Vectors of PhytoplasmasPhyllis Weintraub and J\u00fcrgen Gross7. Insect Vector Transmission AssaysDomenico Bosco and Rosemarie Tedeschi8. Molecular Identification of Phytoplasma Vector SpeciesSabrina Bertin and Domenico Bosco9. Dienes' Staining and Light Microscopy for Phytoplasma VisualizationRita Musetti10. DAPI Staining and Fluorescence Microscopy Techniques for PhytoplasmasNancy S. Andrade and Nolberto S. Arismendi11. Visualisation of Phytoplasmas using Electron MicroscopyB. Jean Devonshire12. Automated DNA Extraction for Large Numbers of Plant SamplesNatasa Mehle, Petra Nikolic, Matevz Rupar, Jana Boben, Maja Ravnikar, and Marina Dermastia13. DNA Extraction from Arborescent Monocots and How To Deal With Other Challenging HostsNigel A. Harrison, Robert E. Davis, and Ericka E. Helmick14. Nested PCR and RFLP Analysis Based on the 16S rRNA GeneBojan Duduk, Samantha Paltrinieri, Ing Ming Lee, and Assunta Bertaccini15. PCR and RFLP Analyses Based on the Ribosomal Protein OperonMarta Martini and Ing-Ming Lee16. Tuf and secY PCR Amplification and Genotyping of PhytoplasmasXavier Foissac, Jean-Luc Danet, Sylvie Malembic-Maher, Pascal Salar, Dana Saf\u00e1rov\u00e1, Pavla V\u00e1lov\u00e1, and Milan Navr\u00e1til17. PCR Analysis of Phytoplasmas Based on the secA GeneMatt Dickinson and Jennifer Hodgetts18. Single-Strand Conformation Polymorphism Analysis for Differentiating Phytoplasma StrainsMartina Seruga Music and Dijana Skoric19. Microarrays for Universal Detection and Identification of PhytoplasmasMogens Nicolaisen, Henriette Nyskjold, and Assunta Bertaccine20. T-RFLP for Detection and Identification of Phytoplasmas in PlantsJennifer Hodgetts and Matt Dickinson21. Real-Time PCR for Universal Phytoplasma Detection and QuantificationNynne Meyn Christensen, Henriette Nyskjold, and Mogens Nicolaisen22. A Real-Time PCR Detection System for the Bois Noir and Flavescence Dor\u00e9e Phytoplasmas and Quantification of the Target DNANatasa Mehle, Nina Prezelj, Matjaz Hren, Jana Boben, Kristina Gruden, Maja Ravnikar, and Marina Dermastia23. Real-Time PCR for Specific Detection of Three Phytoplasmas from the Apple Proliferation GroupNatasa Mehle, Petra Nikolic, Kristina Gruden, Maja Ravnikar, and Marina Dermastia24. Reverse Transcription-PCR for Phytoplasma Detection Utilizing Crude Sap ExtractionsPaola Margaria and Sabrina Palmano25. In-Field Diagnostics Using Loop-Mediated Isothermal Amplification (LAMP)Jenny Tomlinson26. DNA Bar-Coding for Phytoplasma IdentificationOlga Makarova, Nicoletta Contaldo, Samanta Paltrinieri, Assunta Bertaccini, Henriette Nyskjold, and Mogens Nicolaisen27. Phylogenetic Analyses of Phytoplasmas Based on Whole-Genome ComparisonHiromi Nishida28. The iPhyClassifier, An Interactive Online Tool for Phytoplasma Classification and Taxonomic AssignmentYan Zhao, Wei Wei, Ing-Ming Lee, Jonathan Shao, Xiaobing Suo, and Robert E. Davis29. Phytoplasma Proteomic AnalysisXianling Ji and Yingping Gai30. Preparation of Phytoplasma Membrane Recombinant ProteinsLuciana Galetto, Majid Siampour, and Cristina Marzach\u00ec31. Phytoplasma Plasmid DNA ExtractionMark T. Andersen and Lia W. Liefting32. Caesium Chloride-Bisbenzimide Gradients for Separation of Phytoplasm","merchants_number":2,"ean":9781627030885,"category_id":103,"size":null,"min_price":177,"low_price_merchant_id":27291482,"ID":4325939,"merchants":["weltbild","euniverse"],"brand":"undefined","slug":"phytoplasma","url":"\/unterhaltung\/produkt\/phytoplasma\/","low_price_merchant_name":"Weltbild"}
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Transgenic Cotton
Part I: Introduction1. Transgenic Cotton: From Biotransformation Methods to Agricultural ApplicationBaohong Zhang Part II: Transformation2. Agrobacterium-mediated Genetic Transformation of CottonBaohong Zhang 3. Biolistic Transformation of Cotton Zygotic Embryo Meristem K. Rajasekaran 4. Novel Pollen Magnetofection System for Transformation of Cotton Plant with Magnetic Nanoparticles ... zur Produkt-Seite
4996532 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvdHJhbnNnZW5pYy1jb3R0b24tMjczNTgzODE4LmpwZw==!aHR0cHM6Ly9pLndlbHRiaWxkLmRlL3AvdHJhbnNnZW5pYy1jb3R0b24tMjczNTgzODE4LmpwZ3x+fGh0dHBzOi8vb3MxLm1laW5lY2xvdWQuaW8vYjEwMTU4L21lZGlhL2ltYWdlL2JlLzQxLzliLzczMTYwNDQyMDAwMDFBXzYwMHg2MDAuanBn","post_title":"Transgenic Cotton","deeplink":"https:\/\/track.adtraction.com\/t\/t?a=1632201226&as=1592767275&t=2&tk=1&url=https:\/\/www.weltbild.ch\/artikel\/x\/_25222138-1","labels":[],"brand_id":1,"post_content":"Part I: Introduction1. Transgenic Cotton: From Biotransformation Methods to Agricultural ApplicationBaohong Zhang\u00a0Part II: Transformation2. Agrobacterium-mediated Genetic Transformation of CottonBaohong Zhang\u00a03. Biolistic Transformation of Cotton Zygotic Embryo Meristem K. Rajasekaran\u00a04. Novel Pollen Magnetofection System for Transformation of Cotton Plant with Magnetic Nanoparticles as Gene CarriersRui Zhang, Zhigang Meng, Muhammad Ali Abid, and Xiang Zhao\u00a05. Biolistic Transformation of Cotton Embryogenic Cell Suspension CulturesK. Rajasekaran\u00a06. Pollen Tube Pathway-Mediated Cotton Transformation Min Wang, Runrun Sun, Baohong Zhang, and Qinglian Wang\u00a07. Embryogenic Calli Explants and Silicon Carbide Whisker-mediated Transformation of Cotton (Gossypium hirsutum L.) Muhammad Arshad and Shaheen Asad\u00a0Part III: Genome Editing and Vigs8. Genome Editing in Cotton Using CRISPR\/Cas9 SystemChao Li and Baohong Zhang\u00a09. Tobacco Rattle Virus Induced Gene Silencing in CottonCaiping Cai, Xinyu Wang, Baohong Zhang, and Wangzhen Guo \u00a0Part IV:\u00a0 Detection10. Investigating Transgene Integration and Organization in Cotton (Gossypium hirsutum L.) GenomeJun Zhang and Yan Hong\u00a011. Estimating the Copy Number of Transgenes in Transformed Cotton by Real-time Quantitative PCRChengxin Yi and Yan Hong\u00a012. Development of an Enzyme-linked Immunosorbant (ELISA) Assay for the Detection of GM Protein in GM Crops\/ProduceSuchitra Kamle, Dawei Li, Abhishek Ojha, and Arvind Kumar\u00a013. Screening of Transgenic Cotton Based on a Porous Silicon Biosensor\u00a0 Liangliang Chen, Peng Li, Xiaoyi Lv, and Ji Ma\u00a014. YC3.60-based Imaging Analysis on Calcium Level in Cotton CellsMi Zhang, Jianyan Zeng, Huizhen Cao, and Yan Pei15. A Simple and Rapid Method for Determining Transgenic Cotton Plants Using a Marker GeneBaohong Zhang, Hongmei Wang, Fang Liu, and Qinglian Wang\u00a016. A Grafting Technique for Efficiently Transplanting Transgenic Regenerated Plants of CottonMin Wang, Qinglian Wang, and Baohong Zhang\u00a017. Inheritance of Transgenes in Transgenic Bt lines Resistance to Helicoerpa armigera in Upland CottonBaolong Zhang, Wangzhen Guo, and Tianzhen Zhan\u00a0Part V: Application18. Cotton Hairy Root Culture as an Alternative Tool for Cotton Functional GenomicsHee Jin Kim\u00a019. Overexpression of miRNA in Cotton via Agrobacterium-mediated TransformationMin Wang, Runrun Sun, Qinglian Wang, and Baohong Zhang\u00a020. Development of Transgenic CryIA(c)+GNA Cotton Plants via Pollen Tube Pathway Method Confers Resistance to Helicoverpa armigera and Aphis gossypii GloverZhi Liu, Zhen Zhu, and Tianzhen Zhang\u00a021. Next Generation Transgenic Cotton: Pyramiding RNAi with Bt Counters Insect ResistanceWei Ma and Tianzhen Zhang\u00a022. Genetic Transformation of Cotton with the Harpin-encoding Gene hpaXoo of Xanthomonas oryzae pv. Oryzae and Evaluation of Resistance against Verticillium WiltWeiguo Miao and Jingsheng Wang\u00a023. Development of Insect-resistant Transgenic Cotton with Chimeric TVip3A* Accumulating in ChloroplastsJiaheWu and Yingchuan Tian\u00a024. Development of Virus Resistance Transgenic Cotton using Cotton Leaf Curl Virus Antisense \u00dfC1 GeneS.S. Sohrab\u00a0Part VI:\u00a0 Risk Assessment25. Determining Pollen-mediated Gene Flow in Transgenic CottonXiaoping Pan\u00a0","merchants_number":2,"ean":9781493989515,"category_id":103,"size":null,"min_price":177,"low_price_merchant_id":27291482,"ID":4996532,"merchants":["weltbild","euniverse"],"brand":"undefined","slug":"transgenic-cotton","url":"\/unterhaltung\/produkt\/transgenic-cotton\/","low_price_merchant_name":"Weltbild"}
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CRISPR Gene Editing
Part I: Methods for CRISPR-gRNA Design and Quantification of Activity 1. CRISPR-gRNA Design Maria Pallarès Masmitjà, Nastassia Johanna Knödlseder, and Marc Güell 2. Tracking CRISPR's Footprints Lin Lin and Yonglun Luo 3. Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER Eva Karina Brinkman and Bas van Steensel 4. Fast and Quantit... zur Produkt-Seite
4908905 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMWEvNTkvMzgvNzUwOTAxNjQwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvMWEvNTkvMzgvNzUwOTAxNjQwMDAwMUFfNjAweDYwMC5qcGd8fnxodHRwczovL2kud2VsdGJpbGQuZGUvcC9jcmlzcHItZ2VuZS1lZGl0aW5nLTI3MzU3MjA4MS5qcGc=","post_title":"CRISPR Gene Editing","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9781493991693&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Fmedizin-pharmazie%2F378875%2Fcrispr-gene-editing-methods-and-protocols%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"Part I: Methods for CRISPR-gRNA Design and Quantification of Activity\u00a01. CRISPR-gRNA Design\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Maria Pallar\u00e8s Masmitj\u00e0, Nastassia Johanna Kn\u00f6dlseder, and Marc G\u00fcell\u00a02. Tracking CRISPR's Footprints\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Lin Lin and Yonglun Luo\u00a03. Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Eva Karina Brinkman and Bas van Steensel\u00a04. Fast and Quantitative Identification of Ex Vivo Precise Genome Targeting-Induced Indel Events by IDAA\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Saskia K\u00f6nig, Yang Zhang, Hans Heugh Wandall, Claudio Mussolino, and Eric Paul Bennett\u00a05. Functional Evaluation of CRISPR Activity by the Dual-Fluorescent Surrogate System: C-Check\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Lin Lin and Yonglun Luo\u00a0Part II: Methods for CRISPR Delivery\u00a06. CRISPR-Cas9 Delivery by Artificial Virus (RRPHC)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Suleixin Yang, Qinjie Wu, Yuquan Wei, and Changyang Gong\u00a07. Production and Validation of Lentiviral Vectors for CRISPR\/Cas9 Delivery\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Laura Barrett Ry\u00f8, Emil Aagaard Thomsen, and Jacob Giehm Mikkelsen\u00a08. Rapid and Simple Screening of CRISPR Guide RNAs (gRNAs) in Cultured Cells Using Adeno-Associated Viral (AAV) Vectors\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Julia Fakhiri, Manuela Nickl, and Dirk Grimm\u00a09. Electroporation-Based CRISPR\/Cas9 Gene Editing Using Cas9 Protein and Chemically Modified sgRNAs\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Anders Laustsen and Rasmus O. Bak\u00a0Part III: CRISPR Gene Editing in Human iPSCs\u00a010. Efficient Gene Editing of Human Induced Pluripotent Stem Cells Using CRISPR\/Cas9\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Saniye Yumlu, Sanum Bashir, J\u00fcrgen Stumm, and Ralf K\u00fchn\u00a011. Editing the Genome of Human Induced Pluripotent Stem Cells Using CRISPR\/Cas9 Ribonucleoprotein Complexes\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Michaela Bruntraeger, Meg Byrne, Kathleen Long, and Andrew R. Bassett\u00a012. Conditional Gene Knockout in Human Cells with Inducible CRISPR\/Cas9\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Kirsten E. Snijders, James D. Cooper, Ludovic Vallier, and Alessandro Bertero\u00a0Part IV: CRISPR Gene Editing in Other Cell Types\u00a013. CRISPR\/Cas9 as a Genome Editing Tool for Targeted Gene Integration in CHO Cells\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Daria Sergeeva, Jose Manuel Camacho-Zaragoza, Jae Seong Lee, and Helene Faustrup Kildegaard\u00a014. Rapid and Efficient Gene Deletion by CRISPR\/Cas9\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Signe Neldeborg, Lin Lin, Magnus Stougaard, and Yonglun Luo\u00a015. Genome Editing in Mice\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Lisbeth Ahm Hansen and Ernst-Martin F\u00fcchtbauer\u00a016. CRISPR\/Cas9-Mediated Gene Tagging: A Step-by-Step Protocol\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Xi Xiang, Conghui Li, Xi Chen, Hongwei Dou, Yong Li, Xiuqing Zhang, and Yonglun Luo\u00a017. Gene Editing in Primary Cells of Cattle and Pig\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Petra Vochozkova, Kilian Simmet, Eva-Maria Jemiller, Annegret W\u00fcnsch, and Nikolai Klymiuk\u00a0Part V: CRISPR Gene Therapy and Screening\u00a018. Toward In Vivo Gene Therapy Using CRISPR\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Kristian Alsbjerg Skipper and Jacob Giehm Mikkelsen\u00a019. CRISPR Gene Therapy of the Eye: Targeted Knockout of Vegfa in Mouse Retina by Lentiviral Delivery\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Andreas Holmgaard, Sidsel Alsing, Anne Louise Askou, and Thomas J. Corydon\u00a020. In Vivo Editing of the Adult Mouse Liver Using CRISPR\/Cas9 and Hydrodynamic Tail Vein Injection\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Francesco Niola, Frederik Dagn\u00e6s-Hansen, and Morten Fr\u00f6din\u00a021. CRISPR-Based Lentiviral Knockout Libraries for Functional Genomic Screening and Identification of Phenotype-Related Genes\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Emil Aagaard Thomsen and Jacob Giehm Mikkelsen","merchants_number":2,"ean":9781493991693,"category_id":103,"size":null,"min_price":178,"low_price_merchant_id":70255345,"ID":4908905,"merchants":["euniverse","weltbild"],"brand":"undefined","slug":"crispr-gene-editing","url":"\/unterhaltung\/produkt\/crispr-gene-editing\/","low_price_merchant_name":"eUniverse"}
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Dermal Drug Selection and Development
CHAPTER 1. INTRODUCTION 71.1. Developing a new medicine 1.2. Key risks at the candidate selection stage 1.3. Attrition in the pharmaceutical industry 1.4. Evolution of the Pharma R&D over the last 2 decades 1.5. Pharma R&D productivity in decline 1.6. Cost of Pharma R&D and cost up to Candidate selection 1.7. Increased risks to develop a topical drug 1.8. Increased opportunities to de... zur Produkt-Seite
4862573 {"price-changing":0,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvYWIvYjEvZmQvNjUwOTIzNzQwMDAwMUFfNjAweDYwMC5qcGc=!aHR0cHM6Ly9vczEubWVpbmVjbG91ZC5pby9iMTAxNTgvbWVkaWEvaW1hZ2UvYWIvYjEvZmQvNjUwOTIzNzQwMDAwMUFfNjAweDYwMC5qcGc=","post_title":"Dermal Drug Selection and Development","deeplink":"https:\/\/cct.connects.ch\/tc.php?t=116298C1969900829T&subid=9783319595030&deepurl=https%3A%2F%2Feuniverse.ch%2Fbuecher%2Fmathematik-naturwissenschaft-technik%2Ftechnik%2F455095%2Fdermal-drug-selection-and-development-an-industrial-perspective%3FsPartner%3Dtoppreise","labels":[],"brand_id":1,"post_content":"CHAPTER 1. INTRODUCTION 71.1. Developing a new medicine 1.2. Key risks at the candidate selection stage 1.3. Attrition in the pharmaceutical industry 1.4. Evolution of the Pharma R&D over the last 2 decades 1.5. Pharma R&D productivity in decline 1.6. Cost of Pharma R&D and cost up to Candidate selection 1.7. Increased risks to develop a topical drug 1.8. Increased opportunities to develop a topical drug CHAPTER 2. CHOOSING THE TOPICAL DRUG CANDIDATE : AN HISTORICAL OVERVIEW 192.1. The pragmatic topical drug development approach: An existing oral\/systemic drug is further developed as a topical 2.2. Moving towards improved topical drug candidate selection processes: Use of in vivo models2.3. Historical topical drug candidate selection summary CHAPTER 3. KEY FACTORS AFFECTING THE EFFICACY OF A TOPICAL DRUG CANDIDATE: LEARNINGS FROM PAST TOPICAL DRUG DEVELOPMENT 313.1. Skin barrier condition vs. \"Easiness\" of topical drug development 3.2. Drug potency and clinical efficacy CHAPTER 4. TOPICAL VS ORAL\/SYSTEMIC DRUG DISCOVERY 404.1. Drug Discovery Evolution 4.2. Oral\/Systemic Drug Discovery 4.3. Topical Drug Discovery 4.4. The Two Key Differences in discharging risk in between the Oral\/Systemic and Topical Drug Discovery Processes 4.5. Consequences for the Preclinical Stage: \"Maximising the Percutaneous Flux\" 4.6. What can be learned from the Oral Drug Development Process? CHAPTER 5. ASSESSING DRUG CONCENTRATION IN SKIN: DIRECT AND INDIRECT METHODS 525.1. Direct Methods 5.2. Indirect Methods 5.3. Potential Use of the various skin PharmacoKinetic Sampling Methods, Comparisons of the Methods and Consequences 5.4. Using the Percutaneous Flux or the Plasma concentration as surrogate measurement of skin concentration CHAPTER 6. ASSESSING TOPICAL EFFICACY 726.1. Assessing efficacy and dose prediction for a systemic target 6.2. In vivo PD Models: 6.3. Conclusion CHAPTER 7. ASSESSING THE THERAPEUTIC INDEX 867.1. Introduction 7.2. A \"crude\" Approach: Comparing the mass of target tissue with total body mass 7.3. Calculated Approach 7.4. Comparative Approach CHAPTER 8. TOPICAL VEHICLE SELECTION: MYTHS AND REALITY 938.1. Introduction : 8.2. Skin Penetration Enhancement 8.3. Retention in Skin 8.4. For each compound, a specific formulation: A must ? 8.5. Vehicle Aesthetics 8.6. Drug formulated as a dispersion or as a solution? 8.7. Conclusion CHAPTER 9. TOPICAL DRUG DEVELOPMENT STRATEGIES 1079.1. Option#1: Clinical molecule repurposing - Developed drug for a non systemic indication on a new target class 9.2. Option#2: Full lead optimization - New drug from a new mechanism of action for a topical application 9.3. Option#3: \"Me better\" - Improved drug for a known topical target class 9.4. Option#4: Chemical Series Repurposing - Advanced lead optimized chemicals series screened against for a topical indication CHAPTER 10. TOPICAL DRUG CANDIDATE SELECTION CRITERIA AND CASCADE 11110.1. General principles: Discharging risk 10.2. Medicinal chemistry and chemical space 10.3. Potency 10.4. Percutaneous Flux 10.5. Pharmacological Kinetics Response 10.6. Preclinical Proof of Concept 10.7. Solution Stability - Water Stability 10.8. UV Absorption 10.9. Local Irritation 10.10. Systemic Effect (Clearance & Protein Binding) 10.11. Other criterias not important for a topical candidate 10.12. Comparison of the criterias used to select an oral\/systemic candidate and a topical one 10.13. Example of candidate selection cascade when repurposing a whole chemical series CHAPTER 11. SELECTING A DERMAL DRUG CANDIDATE: SOME USEFUL QUOTATIONS AND RULES 127CHAPTER 12. CONCLUSIONS AND PERSPECTIVES 131","merchants_number":1,"ean":9783319595030,"category_id":103,"size":null,"min_price":178,"low_price_merchant_id":70255345,"ID":4862573,"merchants":["euniverse"],"brand":"undefined","slug":"dermal-drug-selection-and-development","url":"\/unterhaltung\/produkt\/dermal-drug-selection-and-development\/","low_price_merchant_name":"eUniverse"}
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Molecular Toxicology Protocols
Part I. Toxicoproteomics1. Array-Based Immunoassays with Rolling-Circle Amplification DetectionKatie Partyka, ShuangshuangWang, Ping Zhao, Brian Cao, and Brian Haab2. Analysis of Protein Changes Using Two Dimensional Difference Gel ElectrophoresisWeimin GaoPart II. Toxicant-Induced Inflammation3. Assessment of Pathological and Physiological Changes in Mouse Lung Through Bronchoalveola... zur Produkt-Seite
4394486 {"price-changing":null,"image":"https:\/\/image.vergleiche.ch\/small\/aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTIwMDk5MjA1X3BMeVE0Ry1wbmc=!aHR0cHM6Ly9jNC1zdGF0aWMuZG9kYXguY29tL3YyLzE4MC0xODAtMTIwMDk5MjA1X3BMeVE0Ry1wbmd8fnxodHRwczovL29zMS5tZWluZWNsb3VkLmlvL2IxMDE1OC9tZWRpYS9pbWFnZS9iZS82OS9hMi80MTc5OTkxNjAwMDAxQV82MDB4NjAwLmpwZw==","post_title":"Molecular Toxicology Protocols","deeplink":"https:\/\/www.awin1.com\/pclick.php?p=22948345429&a=401125&m=11816&pref1=9781627037389","labels":[],"brand_id":1,"post_content":"Part I. Toxicoproteomics1. Array-Based Immunoassays with Rolling-Circle Amplification DetectionKatie Partyka, ShuangshuangWang, Ping Zhao, Brian Cao, and Brian Haab2. Analysis of Protein Changes Using Two Dimensional Difference Gel ElectrophoresisWeimin GaoPart II. Toxicant-Induced Inflammation3. Assessment of Pathological and Physiological Changes in Mouse Lung Through Bronchoalveolar LavageYuanpu Peter Di4. Analysis of Clinical and Biological Samples Using Microsphere-Based Multiplexing Luminex SystemYingze Zhang, Rahel Birru, and Y. Peter DiPart III. Gene Promoter Methylation5. Detection of DNA Methylation by MeDIP and MBDCap Assays: An Overview of TechniquesHang-Kai Hsu, Yu-I Weng, Pei-Yin Hsu, Tim H.-M. Huang, and Yi-Wen Huang6. Screening of DNA Methylation Changes by Methylation-Sensitive Random Amplified Polymorphic DNA-Polymerase Chain Reaction (MS-RAPD-PCR)Kamaleshwar P. SinghPart IV. Array Technologies7. Strategies for Measurement of Biotransformation Enzyme Gene ExpressionMarjorie Romkes and Shama C. Buch8. Genotyping Technologies: Application to Biotransformation Enzyme Genetic Polymorphism ScreeningMarjorie Romkes and Shama C. Buch9. TaqMan Fluorogenic Detection System to Analyze Gene Transcription in Autopsy MaterialKaori Shintani-Ishida, Bao-Li Zhu, and Hitoshi MaedaPart V. Analysis of DNA Adducts10. 32P-Postlabelling Analysis of DNA AdductsDavid H. Phillips and Volker M. Arlt11. Modification of the 32P-Postlabeling Method to Detect a Single Adduct Species as a Single SpotMasako Ochiai, Takashi Sugimura, and Minako Nagao12. DNA Isolation and Sample Preparation for Quantitation of Adduct Levels by Accelerator Mass SpectrometryKaren H. Dingley, Esther A. Ubick, John S. Vogel, Ted J. Ognibene, Michael A. Malfatti, Kristen Kulp, and Kurt W. Haack13. Analysis of DNA Strand Cleavage at Abasic SitesWalter A. Deutsch and Vijay HegdePart VI. Detection of Chromosomal and Genome-Wide Damage14. Premature Chromosome Condensation in Human Resting Peripheral Blood Lymphocytes without Mitogen Stimulation for Chromosome Aberration Analysis Using Specific Whole Chromosome DNA Hybridization ProbesRupak Pathak and Pataje G. S. Prasanna15. Mutagen Sensitivity as Measured by Induced Chromatid Breakage as a Marker of Cancer RiskXifeng Wu, Yun-Ling Zheng, and T. C. Hsu16. Pulsed-Field Gel Electrophoresis Analysis of Multicellular DNA Double-Strand Break Damage and RepairNina Joshi and Stephen G. GrantPart VII. Detection and Characterization of Surrogate Gene Mutation17. Detection of Pig-a Mutant Erythrocytes in the Peripheral Blood of Rats and MiceVasily N. Dobrovolsky, Xuefei Cao, Javed A. Bhalli, and Robert H. Heflich18. The Blood-Vased Glycophorin A Human In vivo Somatic Mutation AssayNicole T. Myers and Stephen G. Grant19. Flow Cytometric Quantification of Mutant T Cells with Altered Expression of the T-Cell Receptor: Detecting Somatic Mutants in Humans and MiceSeishi Kyoizumi, Yoichiro Kasunoki, and Tomonori Hayashi20. Analysis of in Vivo Mutation at the HPRT and TK Genes of Mouse LymphocytesVasily N. Dobrovolsky, Joseph G. Shaddock, and Robert H. Heflich21. Quantifying In Vivo Somatic Mutations Using Transgenic Mouse Model SystemsRoy R. Swiger22. The Human T-Cell Cloning Assay: Identifying Genotypes Susceptible to Drug Toxicity and Somatic MutationSai-Mei Hou23. Molecular Analysis of HPRT Mutations in Human LymphocytesPhouthone Keohavong, Liqiang Xi, Stephen G. and Grant24. Simultaneous Quantification of t(14,18) and HPRT Exon 2\/3 Deletions in Human LymphocytesJames C. FuscoePart VIII. Detection and Characterization of Cancer Gene Mutation25. Mutation Screening of the TP53 Gene by Temporal Temperature Gel ElectrophoresisTherese S\u00f8rlie, Hilde Johnson, Phuong Vu, Guro Elisabeth Lind, Ragnhild Lothe, and Ann","merchants_number":2,"ean":9781627037389,"category_id":103,"size":null,"min_price":146.69999999999998863131622783839702606201171875,"low_price_merchant_id":1087639,"ID":4394486,"merchants":["dodax","euniverse"],"brand":"undefined","slug":"molecular-toxicology-protocols","url":"\/unterhaltung\/produkt\/molecular-toxicology-protocols\/","low_price_merchant_name":null}
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