Vaccines for Invasive Fungal Infections

Part I: Discovery and Testing of Vaccine Candidates 1. Mouse Immunization with Radioattenuated Yeast Cells of Paracoccidioides brasiliensis            Estefânia Mara do Nascimento Martins and Antero Silva Ribeiro de Andrade 2. Heat-Killed Yeast as a Pan-Fungal Vaccine            Marife Martinez, Karl V. Clemons, and David A. Stevens 3. Immunoinformatics as a Tool for New Antifungal Vaccines            Rupanjali Chaudhuri and Srinivasan Ramachandran 4. Rational Design of T Lymphocyte Epitope-Based Vaccines Against Coccidioides Infection            Brady J. Hurtgen and Chiung-Yu Hung 5. Identification of Fungal T Cell Epitopes by Mass Spectrometry-Based Proteomics            Bernd Roschitzki and Salomé LeibundGut-Landmann 6. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells            Shanjana Awasthi 7. DNAhsp65 Vaccine as Therapy Against Paracoccidioidomycosis            Alice M. Ribeiro, André C. Amaral, Maria Sueli S. Felipe, and Anamelia L. Bocca 8. Idiotypic Antifungal Vaccination: Immunoprotection by Antiidiotypic Antibiotic Antibodies            Luciano Polonelli, Walter Magliani, and Stefania Conti 9. Peptide Vaccine Against Paracoccidioidomycosis            Carlos P. Taborda and Luiz R. Travassos 10. Methodology for Anti-Cryptococcal Vaccine Development            Ashok K. Chaturvedi and Floyd L. Wormley Jr. Part II: Design and Delivery 11. Beta-Glucan Particles as Vaccine Adjuvant Carriers            Zeynep Mirza, Ernesto R. Soto, Fusun Dikengil, Stuart M. Levitz, and Gary R. Ostroff 12. Th1-Inducing Agents in Prophylaxis and Therapy for Paracoccidioidomycosis            Thiago Aparecido da Silva, Fabrício Freitas Fernandes, Taise Natali Landgraf, Ademílson Panunto-Castelo, and Maria Cristina Roque-Barreira 13. Nanoparticle-Based Mycosis Vaccine            Swaleha Zubair, Asim Azhar, Nazoora Khan, Ejaj Ahmad, Mohd Ajmal, and Owais Mohammad 14. Yeast Expressing Gp43 Protein as a Vaccine Against Paracoccidioides brasiliensis Infection            Aline Ferreira Oliveira and Paulo S.R. Coelho 15. Vaccination with Phage-Displayed Antigenic Epitope            Yicun Wang and Li Wang 16. Preparation of an Oral Vaccine by Proteome Analysis and Molecular Display Technology            Seiji Shibasaki and Mitsuyoshi Ueda Part III: Endpoint Assessment 17. Precise and Efficient In-Frame Integration of an Exogenous GFP Tag in Aspergillus fumigatus by a CRISPR System            Chi Zhang and Ling Lu 18. Endpoint Assessment in Rabbit Models of Invasive Pulmonary Aspergillosis and Mucormycosis            Vidmantas Petraitis, Ruta Petraitiene, William Hope, and Thomas J. Walsh Part IV: Mechanism of Vaccine Protection 19. CD4+ T Cells Mediate Aspergillosis Vaccine Protection            Diana Diaz-Arevalo and Markus Kalkum 20. T-Cell-Mediated Cross-Protective Immunity            Nina Khanna and Claudia Stuehler 21. Assessment of Post-Vaccination Phagocytic Activation Using Candida albicans Killing Assays            Wenqing Li and Yan Hu 22. Immunization with Antigen-Pulsed Dendritic Cells Against Highly Virulent Cryptococcus gattii Infection: Analysis of Cytokine-Producing T Cells            Keigo Ueno, Makoto Urai, Shogo Takatsuka, Masahiro Abe, Yoshitsugu Miyazaki, and Yuki Kinjo Part V: Translation to Clinical Use 23. Testing Antifungal Vaccines in an Animal Model of Invasive Candidiasis and in Human Mucosal Candidiasis            Esther Segal... Mehr