The Role of Rhes Protein in the Dopaminergic System of Rodents

Rhes is a new protein that is highly expressed in thestriatal system of rodents. In the present book, itis described experimental work about the role of thisprotein in behaviors mediated by the striataldopaminergic system. Some of the behavioralparadigms described are stereotypy, anxiety and basallevels of activity. The mutant mice model used isthe rhes ko mice. Female groups are included for allthe experiments. Very interesting gender differencesare found in anxiety and stereotypy. The presentwork give evidence of the role of rhes protein indopamine receptor supersensitivity, this is relevantfor conditions like schizophrenia, Parkinson disease,ADHD and others. This book represents one of the fewworks that have been performed in the role of rhesprotein in behavioral neuroscience.... Mehr