The EBMT Handbook

Part I. Chapter. 1 HSCT: Historical perspectiveStorb, RChapter. 2 The EBMT: History, present & futureApperley, J,  Gratwohl, A, Mohty, MChapter. 3 The donor registries (organization, regulation, international search...)Madrigal, A, Evseeva, IrinaChapter. 4 The HSCT Unit (minimal requirements, data manager trasplant coordinator)Aljurf, M, Niederwieser, Dietger, Rasheed, WalidChapter. 5 JACIE accreditation of HSCT programsSaccardi, RChapter. 6Statistics in HSCT and Cellular TherapiesLabopin, M, Iacobelli, S, de Wreede, Liesbeth, Szydlo, RichardPart II. Chapter. 7 Biological properties of HSC: scientific basis for HSCTChabannon, C , Aiuti, MChapter. 8 Biological properties of cells other than HSC (adaptative, abT, Treg, DC. Innete gdT, IELs MSC, NK)Toubert, A, Koehl, U, Bondanza, AChapter. 9 Histocompatibility (main concepts on HLA)K. Fleischhauer, SpieringsChapter. 10 Clinical & biological concepts for mastering Immune reconstitution after HSCTBoelens, J, Kuball, JPart III. Chapter. 11 Evaluation and counselling of candidatesRambaldi, AChapter. 12 Donor selection  for adults and pediatricsAyuk, F, Balduzzi, AChapter. 13 Conditioning (MAC, RIC, NMA, including TBI)Nagler, AChapter. 14 Bone marrow harvestGorin, ClaudeChapter. 15 Mobilization and collection of HSCHübel, KChapter. 16 Collection of HSC in childrenPeters, C, Witt, VolkerChapter. 17 Processing, cryopreserving, and controlling the quality of HSCWuchter, PatrickChapter. 18 Procurement and management of cord bloodRocha, V, Querol, SChapter. 19 Graft manipulationHandgretinger, RChapter. 20 Documentation of engraftment and chimerism after HSCTBader, PChapter. 21 Short and long term controls after HSCTShimoni, APart IV. Chapter. 22 Vascular accessCesaro, SChapter. 23 Transfusion supportSchrezenmeier, HChapter. 24 Fluid and electrolyte managementMasszi, T, Baumgartner, AnnicChapter. 25 GVHD prophylaxis (immunosuppression)Socié, GChapter. 26 Management ATG (SIRS)F. BonifaziChapter. 27 Infections control and isolation proceduresMikulska, M  Chapter. 28 Pain managementAhmedzai, SHChapter. 29 Specific aspects of management in childrenCastagnola, Elio, Riccardi, FChapter. 30 Vaccinationsde la Cámara, RafaChapter. 31 Psychological supportMoreno, E , Schulz-Kindermann, F , Polomeni, AliceChapter. 32 Relevant pharmacological interactionBauters, TChapter. 33 Role of nursing in HSCTBabic, A, Murray, JChapter. 34 Ethical issues in HSCTDalle, JH, El-Ghariani, KPart V. Chapter. 35 Quality assessment of life after HSCT for pediatric and adultsBarata, Anna, Jim, HeatherChapter. 36 Neutropenic feverMikulska, M  Chapter. 37 Bacterial infectionsAverbuch, DChapter. 38 Invasive fungal infectionsMaertens, JChapter. 39 Viral infections (CMC, EVB, VZV, HSV, HHV6, Resp. V, HCV, HBV...) & anti-viral cell therapyLjungman, P, Styczynski, J, Einsele, HermannChapter. 40 Other infections in HSCT (Tuberc, Toxo, PCJ, Noc, List.)Martino, RChapter. 41 Bleeding and thrombotic complicationsSavani, BChapter. 42 Graft failureValcárcel , D, Sureda, AChapter. 43 Early complications of endothelial originCarreras, EChapter. 44 Acute GvHDGreinix, H, Holler, E, Zeiser, RChapter. 45 Chronic GvHDWolff, D, Lawitschka, AChapter. 46 Post-transplant lymphoproliferative syndromesStyczynski, J , Giebel, SChapter. 47 Iron overloadAngelucci, EChapter. 48 Secondary neoplasia (other than PTLPS)Tichelli, APart VI. Chapter. 49 Specific organ complications: Ocular / oral / pulmonary / hepaticRuutu, T, Hashmi, SChapter. 50 Gastrointestinal complicationsBasak, GChapter. 51 Hemorrhagic cystitis and renal dysfunctionCesaro, SChapter. 52 Pulmonary complicationsCarreras, EChapter. 53 Neurological complicationsDuléry, RChapter. 54 Specific organ complications: Skin, hair, musculoskeletalAyuk, F, Savani, BChapter. 55 Cardiovascular diseases and metabolic syndromeSnowden, J, Greenfield, DChapter.  56 Endocrine, fertility and sexual healthSalooja, N, Shoham,  Z, Balduzzi, APart VII. Chapter. 57 Monitoring MRD in ALLBader, P, Ossenkoppele, GChapter. 58 Preventing/treating relapse with drugsKröger, N, Mohty, MChapter. 59 Preventing relapse by mean cells (DLI, aBT, subsets, tumour specific T cells) Kuball, J, Falkenburg, JH Fred, Kolb, HJ, Locatelli, FChapter. 60 Cellular therapy (CAR T, TCR T, suicide genes) with management and side effectsBonini, C, Hudecek, Michael, Fehse, Boris, Bondanza, AChapter. 61 Mechanisms of Immune resistance and overcoming immune resistance (checkpoint...)Dazzi, F, Vago, LChapter. 62 Regulatory Aspects of ATMP versus minimally manipulated immune cellsMc Grath, E, Chabannon, C Part VIII. Chapter. 63 At-home HSCTFernández-Avilés, FChapter. 64 Cord blood HSCT (adults & children)Veys, P, Rocha, V, Sanz, JChapter. 65 Haploidentical HSCT (TCD and TC-repleted)Ciceri, F , Bacigalupo, AChapter. 66 Photopheresis in adults and pediatricsGreinix, H, Gennery, AChapter. 67 Pediatric aspects of haploidentical HSCTGennery, A, Bertaina, A, Slatter, M, Lankester, A, Albert, MChapter. 68 Overweight and obese patientsLangebrake, C Chapter. 69 HSCT in Elderly patiensDuarte, RPart IX. Chapter. 70 EBMT indication for allo and auto HSCTBOARDChapter. 71 AML in adults (incl APL)Nagler, A, Cornelissen, J, Craddock, C, Sanz, MAChapter. 72 AML in childrenGibson, B , Sauer, MChapter.  73 ALL in adultsMarks, D , Stelljes, MChapter. 74 ALL in children and adolescentsPeters, C, Locatelli, F, Bader, PChapter. 75 Myelodysplastic syndromesde Witte, T, Robin, MChapter. 76 Refractory Anemia and JMML in childrenNiemeyer, CMChapter. 77 Myelodysplastic/myeloproliferative syndromesOnida, F, Chalandon, Y Chapter. 78 Myeloproliferative neoplasms (CML, PM, other MPN)Olavarria E, Kröger, NChapter. 79 Severe aplastic anemia and PNHDufour C, Peffault de la Tour,  R, Risitano, Antonio MariaChapter. 80 Fanconi anemia and other hereditary BMF syndromesFioredda, F, Strahm, B, Diaz de Heredia, Cristina, Dalle, JH, Bierings, MarcChapter. 81 Hemoglobinopathies (SCA)Gluckman, E, Abboud, MiguelChapter. 82 Multiple myelomaMohty, M, Blade, Joan, Bruno, BChapter.  83 Systemic light chain amyloidosisSchönland, S, Minnema, MChapter. 84 POEMS syndrome and disease produced by other monoclonal IgsCook, G, Rovira, MChapter. 85 Low grade NHL (follicular, MALT, MW)Robinson, S, Kyriacou, CChapter. 86 Chronic lymphoid leukemiaDreger, P, Schetelig, JohannesChapter. 87 Diffuse large B cell NHLBazarbachi, A, Schmitz, NChapter. 88 Mantle cell lymphomaDietrich, S, Hermine, OChapter. 89 Other T- and B-aggressive lymphomas (Burkitt, LL, PTCL) & Lymphomas associated to HIVHübel, K, Montoto, SChapter. 90 Hodgkin lymphomaSureda, A, Martinez, CarmenChapter. 91 Primary immunodeficiency diseasesLankester, A, Gennery, A, Albert, MChapter. 92 Inborn error of metabolism and osteopetrosisSchulz, A, Wynn, RChapter.93 Autoimmune diseaseSnowden, J, Rovira, M, Alexander, T , Sharrack, B , Farge, DChapter.94 Solid tumors (adults and children)Lanza, F, Ladenstein, RAppendixEBMT RegistryRuiz, C, Hewer... 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