Shorttitle: The development and maintenance of apical seal is desirable and considered to be a major prerequisite to improve the outcome of root canal treatment. Basically, two materials are used in combination for the root canals filling, a semisolid material (gutta-percha) and a sealing cement. Many types and brands of endodontic sealers are commercially available, but none of them fully satisfy all requirements and able to provide a fluid- tight seal. To address this problem the School of Dental... Mehr