Part I: Regulation and Structure-Function Studies of CK21. Yeast Asf1 protein as modulator of protein kinase CK2 activityAndrea Baier, Ewa Alikowska and Ryszard Szyszka2. Impressions from the conformational and configurational space captured by protein kinase CK2Jennifer Hochscherf, Alexander Schnitzler, Olaf-Georg Issinger and Karsten Niefind3. Structural basis of CK2 regulation by autoinhibitory oligomerizationGraziano Lolli and Roberto Battistutta4. Maize RNA binding protein ZmTGH: a new partner for CK2beta1 regulatory subunitIsabel Cristina Vélez-Bermúdez and Marta RieraPart II: CK2 Control of Organismal and Cellular Functions 5. CK2 in Organ Development, Physiology, and HomeostasisCharina E. Ortega, Lawrence Prince-Wright, and Isabel Dominguez6. Protein kinase CK2, a window into the post-translational regulation of the E(spl)/HES repressors from invertebrates and vertebratesAdam T. Majot, Tyler R. Sizemore, Mohna Bandyopadhyay, Lucas M. Jozwick and Ashok P. Bidwai 7. Tissue specific functions and regulation of protein kinase CK2Sabrina Welker, Christina Servas, Meng Rui, Claudia Götz and Mathias Montenarh8. CK2 function in the regulation of Akt pathwayCristina Girardi and Maria Ruzzene9. Cellular zinc signalling is triggered by CK2Thirayost Nimmanon and Kathryn M. Taylor10. CK2 - A global regulator of cell deathJaneen H. Trembley, Fatima Qaiser, Betsy T. Kren, Khalil Ahmed11. Protein Kinase CK2: Systematic Relationships with Other Post-Translational ModificationsDavid W. Litchfield and Laszlo Gyenis 12. Role for protein kinase CK2 on cell proliferation: Assessing CK2 complex components in the nucleus during the cell cycle progressionMiwako Kato Homma, Takeshi Shibata, Toshiyuki Suzuki, Masato Ogura, Hiroko Kozuka-Hata, Masaaki Oyama, and Yoshimi Homma13. "Genuine" casein kinase: the false sister of CK2 that phosphorylates secreted proteins at S-x-E/pS motifsElena Tibaldi, Giorgio Arrigoni, Giorgio Cozza, Luca Cesaro, Lorenzo A. PinnaPart III: Function of CK2 in Cancer and its Therapeutic Targeting14. Dysregulated expression of Protein kinase CK2 in Renal cancerCaroline Roelants, Sofia Giacosa, Eve Duchemin-Pelletier, Anne McLeer-Florin, Céline Tisseyre, Cédric Aubert, Pierre Champelovier, Jean Boutonnat, Jean Luc Descotes, Jean-Jacques Rambeaud, Valentin Arnoux, Jean-Alexandre Long, Dominique Pasquier, Mathieu Laramas, Maysoun Kassem, Laurence David-Boudet, Laure Schoutteten, Benoit Bestgen, Catherine Pillet, Claude Cochet, Odile Filhol15. Protein Kinase CK2 and Dysregulated Oncogenic Inflammatory Signaling Pathways Etty N. Benveniste, G. Kenneth Gray and Braden C. McFarland 16. CIGB-300: A promising anti-Casein Kinase 2 (CK2) peptide for cancer targeted therapySilvio E. Perea, Yasser Perera, Idania Baladrón, Lidia González, Fernando Benavent, Hernán G. Fariña, Idrián García, Arielis Rodríguez, Vilcy Reyes, Yanelda García, Roberto Gómez, Daniel F. Alonso, Carmen Valenzuela17. Targeting CK2 for Cancer Therapy Using a Nanomedicine ApproachKhalil Ahmed, Gretchen Unger, Betsy T. Kren, Janeen H. Trembley Part IV: Studies Involving CK2 Small Molecule Inhibitors 18. Screening of DTP compound libraries for CK2 inhibitors with focus on natural productsTine D. Rasmussen, Barbara Guerra and Olaf-Georg Issinger19. CK2 inhibitors and the DYRK family protein kinasesYoshihiko Miyata20. Sensitivity of protein kinase CK2 to ATP/GTP and specific inhibitors depends on complexity of interacting proteinsAndrea Baier and Ryszard Szyszka... Mehr