1. Methodologies to Identify and Analyze Genetic Polymorphisms for Human Histamine Receptors Stephany Micallef and Astrid Sasse 2. Development, Characterization, and Validation of Anti-Human H3 Receptor Isoform-Specific Antibodies Fiona C. Shenton, Natasha Lethbridge, and Paul L. Chazot 3. Approaches to Recombinant Histamine H3/H4 Receptor Expression in Mammalian Cells Tadeusz Karcz, Urszula Cichon, and Katarzyna Kiec-Kononowicz 4. Histamine H2 Receptor Biased Signaling Methods Natalia Fernández, Carina Shayo, Carlos Davio, and Federico Monczor 5. Ligand-Binding Kinetics on Histamine Receptors Reggie Bosma, Tamara A.M. Mocking, Rob Leurs, and Henry F. Vischer 6. Methods to Study the Molecular Pharmacology of the Histamine H4 Receptor Eléonore W.E. Verweij, Rob Leurs, and Henry F. Vischer 7. Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antagonists on Neutrophil Oxidative Burst Ondrej Vasícek, Tomás Perecko, Viera Jancinová, Silvia Pazoureková, Radomír Nosál', and Milan Cíz 8. Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosinophils Marek Grosicki and Katarzyna Kiec-Kononowicz 9. Assessment of the Efficacy of Histamine Receptor Antagonists in Murine Models of Atopic Dermatitis Kristine Roßbach, Hanna Köchling, Tomoki Fukuyama, Jenny Wilzopolski, Manfred Kietzmann, and Wolfgang Bäumer 10. Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cell Imaging to Functional Assays and Electron Microscopy Alessandro Pini, Eleonora Veglia, Cristina Grange, and Arianna Carolina Rosa 11. Histamine and the Kidney: In Vivo Animal Models Alessandro Pini, Eleonora Veglia, and Arianna Carolina Rosa 12. Methodological Approaches to Investigate the Effects of Histamine Receptor Targeting Compounds in Preclinical Models of Breast Cancer Diego J. Martinel Lamas, Melisa B. Nicoud, Helena Sterle, Graciela P. Cricco, Gabriela A. Martin, Graciela A. Cremaschi, Hubert G. Schwelberger, Elena S. Rivera, and Vanina A Medina 13. Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC mRNA Levels Carlos Acosta-Andrade, José L Urdiales, Ignacio Fajardo, and Francisca Sánchez-Jiménez 14. Cerebrospinal Fluid Markers in Neuroinflammation: The Paradigm of Optic Neuritis Dimitrios P. Besinis and Maria C. Anagnostouli 15. In Vivo Diagnostic Procedures for IgE-Mediated Allergic Disorders Christopher Koulias, Xenophon Aggelides, Caterina Chliva, and Michael Makris 16. Dermatological Indications of Antihistamines Chrysovalantis Korfitis, Efstathios Rallis, and Dimitrios Rigopoulos 17. Histamine Quantification in Human Blood Samples Ekaterini Tiligada, Maria Kakolyri, and Madeleine Ennis... Mehr