Part I: General 1. Heterogeneity of Metazoan Cells and Beyond: To Integrative Analysis of Cellular Populations at Single-Cell Level Natasha S. Barteneva and Ivan A. Vorobjev 2. Integrating Analysis of Cellular Heterogeneity in High Content Dose-Response Studies Albert Gough, Tong Ying Shun, D. Lansing Taylor, and Mark Schurdak 3. Image-Based Tracking of Heterogeneous Single Cell Phenotypes Katherin Patsch, Shannon M. Mumenthaler, and Daniel Ruderman Part II: Cytometry in Cellular Heterogeneity Research 4. High-Dimensional Single Cell Analysis with Mass Cytometry Tess Melinda Brodie and Vinko Tosevski 5. Spectral and Imaging Flow Cytometry in Phytoplankton Research Veronika Dashkova, Jeff Clapper, Ivan A. Vorobjev, and Natasha S. Barteneva 6. X-Ray Fluorescence Detected Flow Cytometry Andrew M. Crawford and James E. Penner-Hahn 7. Multiparametric Analysis of Myeloid Populations by Flow Cytometry Sara A. Mathie, Alastair L. Corbin, Hayley L. Eames, and Irina A. Udalova 8. Quantitation of IRF3 Nuclear Translocation in Heterogeneous Cellular Populations from Cervical Tissue Using Imaging Flow Cytometry Radiana T. Trifonova and Natasha S. Barteneva 9. Methods of Study of Neuron Structural Heterogeneity: Flow Cytometry vs. Laser Interferometry Ekaterina Kopeikina, Marina Dukhinova, and Eugene D. Ponomarev 10. Usage of Multiparameter Flow Cytometry to Study Microglia and Macrophage Heterogeneity in the Central Nervous System during Neuroinflammation and Neurodegeneration Marina Dukhinova, Ekaterina Kopeikina, and Eugene D. Ponomarev Part III: Imaging and Spectroscopy Methods in Heterogeneity Studies 11. Analysis of Microtubule Dynamics Heterogeneity in Cell Culture Anara Serikbaeva, Anna Tvorogova, Sholpan Kauanova, and Ivan A. Vorobjev 12. Heterogeneity of Focal Adhesions and Focal Contacts in Motile Fibroblasts Aleena Gladkikh, Anastasia Kovaleva, Anna Tvorogova, and Ivan A. Vorobjev 13. Laser Tweezers Raman Micro-Spectroscopy of Single Cells and Biological Particles Maria Navas-Moreno and James W. Chan Part VI: Metabolic and Molecular Biological Methods in Cell Heterogeneity Tracking 14. Quantification of the Metabolic Heterogeneity in Mycobacterial Cells Through the Measurement of the NADH/NAD+ Ratio Using a Genetically-Encoded Sensor Shabir Ahmad Bhat, Iram Khan Iqbal, and Ashwani Kumar 15. Characterizing Cell Heterogeneity Using PCR Fingerprinting of Surface Multigene Families in Protozoan Parasites Víctor Seco-Hidalgo, Antonio Osuna, and Luis Miguel de Pablos 16. Assessing Carbon Source-Dependent Phenotypic Variability in Pseudomonas putida Pablo I. Nikel and Víctor de Lorenzo Part V: Chromatin and Cell Cycle Heterogeneity 17. The Retinal Pigment Epithelial Cell Line (ARPE-19) Displays Mosaic Structural Chromosomal Aberrations Elizaveta Fasler-Kan, Nijas Aliu, Kerstin Wunderlich, Sylvia Ketterer, Sabrina Ruggiero, Steffen Berger, and Peter Meyer 18. FACS Isolation of Viable Cells in Different Cell Cycle Stages from Asynchronous Culture for RNA-Sequencing Daria M. Potashnikova, Sergey A. Golyshev, Alexey A. Penin, Maria D. Logacheva, Anna V. Klepikova, Anastasia A. Zharikova, Alexey A. Mironov, Eugene V. Sheval, and Ivan A. Vorobjev 19. Measuring Nanoscale Chromatin Heterogeneity with Partial Wave Spectroscopic Microscopy Scott Gladstein, Andrew Stawarz, Luay M. Almassalha, Lusik Cherkezyan, John E. Chandler, Xiang Zhou, Hariharan Subramanian, and Vadim Backman... Mehr