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A combinatorial approach in metal cytotoxic mechanisms condenses the diffuse literature on metal toxicology into an accessible and readable text. It introduces fundamental concepts in mechanistic toxicology and use a functionomic approach to understand the heavy metals cytotoxic mechanism, e.g., the effects of inhibitors or substrates of metabolizing enzyme/transporting pathway and other cellular vital pathways on the loss of cell viability and oxidative stress markers induced by the heavy metals.... Mehr