Redox Proteomics

Methodology and applications of redox proteomics The relatively new and rapidly changing field of redox proteomicshas the potential to revolutionize how we diagnose disease, assessrisks, determine prognoses, and target therapeutic strategies forpeople with inflammatory and aging-associated diseases. Thiscollection brings together, in one comprehensive volume, a broadarray of information and insights into normal and alteredphysiology, molecular mechanisms of disease states, and newapplications of the rapidly evolving techniques ofproteomics. Written by some of the finest investigators in this area, RedoxProteomics: From Protein Modifications to Cellular Dysfunction andDiseases examines the key topics of redox proteomics and redoxcontrol of cellular function, including: * The role of oxidized proteins in various disorders * Pioneering studies on the development of redox proteomics * Analytical methodologies for identification and structuralcharacterization of proteins affected by oxidative/nitrosativemodifications * The response and regulation of protein oxidation in differentcell types * The pathological implications of protein oxidation forconditions, including asthma, cardiovascular disease, diabetes,preeclampsia, and Alzheimer's disease Distinguished by its in-depth discussions, balanced methodologicalapproach, and emphasis on medical applications and diagnosisdevelopment, Redox Proteomics is a rich resource for allprofessionals with an interest in proteomics, cellular physiologyand its alterations in disease states, and related fields.... Mehr